Effect of surgery on the treatment of nystagmus with oculocutaneous albinism
Wang Yuan,Wu Qian,Bai Dayong,Shi Wei,Hu Man,Li Li
National Key Discipline of Pediatrics, Ministry of Education, Department of Ophthalmology, Beijing Children′s Hospital, Capital Medical University, Beijing 100045, China
Objective To evaluate the efficacy of surgery in the treatment of nystagmus with oculocutaneous albinism (OCA). Methods This was a retrospective case series study. Nine nystagmus patients with oculocutaneous albinism who were diagnosed between May 2012 and October 2014 in Beijing Children′s Hospital were enrolled in this study. The age was 4 to 10 years and followed up 6 to 24 months. Patients underwent different types of surgery based on the manifestations of their condition. Best corrected visual acuity (logMAR) and nystagmus waveform were analyzed before and after the surgery. Results Binocular visual acuity increased from 1.1±0.1 preoperatively to 1.0±0.1 postoperatively and the difference was significant (t=5.965, P<0.05). Patients had significant improvements in the frequency (t=6.377, P<0.05) and intensity (t=5.622, P<0.05) of nystagmus waveforms postoperatively but there was no significant improvement in the amplitude of the waveform (t=1.949, P>0.05). Conclusion Surgery for the treatment of nystagmus with OCA can provide expectations of ocular motor and visual results. The different manifestations of the condition should determine the type of surgery.
王媛,吴倩,白大勇,施维,胡曼,李莉. 眼皮肤白化病患儿眼球震颤的手术疗效[J]. 中华眼视光学与视觉科学杂志, 2016, 18(1): 54-58.
Wang Yuan,Wu Qian,Bai Dayong,Shi Wei,Hu Man,Li Li. Effect of surgery on the treatment of nystagmus with oculocutaneous albinism. Chinese Journal of Optometry Ophthalmology and Visual science, 2016, 18(1): 54-58. DOI: DOI:10.3760/cma.j.issn.1674-845X.2016.01.012
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