Glaucoma is common and is a leading cause of irreversible blindness worldwide. The pathological foundation of visual function damage is the death of retinal ganglion cells and the loss of nerve fibers. Ganglion cell death is mainly through cell apoptosis. Its pathophysiological features are the same as with most of the diseases of the nervous system including oxidative stress and ischemia. The mitochondrion is a vital intracellular organelle for retinal cell function and survival.
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