Prediction Accuracy of Intraocular Lens Formulas Using Different Biometers
Yubo Wu1, Songyu Liu2, Rongfeng Liao1
1Department of Ophthalmology, the First Affiliated Hospital of Anhui Medical University, Hefei 230032,
China
2Department of Ultrasound, the First Affiliated Hospital of Anhui Medical University, Hefei 230032, China
Objective: To compare the prediction accuracy of intraocular lens (IOL) formulas using partial coherenceinterferometry (IOLMaster) and applanation ultrasound (AL-3000) assisted corneal topography (TMS-4).Methods: Eyes (n=133) undergoing phacoemulsification cataract surgery with posterior chamber IOLimplantation in our hospital between January 15, 2016 and May 1, 2016 were studied proactively. Axial length(AL), K-value, and anterior chamber depth (ACD) were preoperatively measured using the IOLMaster, AL 3000, and TMS-4. Haigis, Hoffer Q, Holladay I, and SRK/T biometric formulas with optimized constants were used to calculate IOL power. Refractive outcomes were determined by streak retinoscopy and subjective manifest refraction 3 months after the surgeries. Formulas and biometers were evaluated by mean error, standard deviation (SD), range of error, mean absolute error, median absolute error, 95% confidence interval of mean absolute error,and percentage of eyes within ±0.5 diopter (D), ±1.0 D, and ±2.0 D of prediction. F-tests were used to comparethe results between formulas and biometers. Results: The SDs of the Haigis, Hoffer Q, Holladay I, and SRK/T formulas using IOLMaster were 0.468, 0.591, 0.613, and 0.624. The SDs of Hoffer Q, Holladay I, and SRK/T were significantly larger than that of Haigis (F=9.632, 11.984, 9.215, all P<0.05). SDs of the AL-3000 assisted with TMS-4 were 0.580, 0.624, 0.642, and 0.700, respectively. The SD of SRK/T was significantly larger than that of Haigis (F=5.365, P=0.021). In short eyes, the SD of SRK/T was significantly larger than that of Haigis (F=7.071, P=0.012) using IOLMaster. In long axis eyes, the SD of SRK/T was significantly larger than that of Haigis (F=6.681, P=0.012) using IOLMaster, with hyperopic shifts of 0.44 D and 0.43 D in Hoffer Q and Holladay I. Conclusions: The Haigis formula with measurements using the IOLMaster was promising in eyes with all ranges of AL.
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