Effects of sedentary behavior and physical activity on the caliber of retinal microvessels in Chinese adults
Xueping Zhang,Chimei Liao,Wei Zhang,Hongfei Huang,Mingguang He
Department of Ophthalmology, the Eleventh People's Hospital, Guangzhou 510530, China
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University,Guangzhou 510060, China
Objective: To explore the association between sedentary behavior, physical activity and retinal microvessels caliber in normal people. Methods: In this cross-sectional study, 6 560 participants, age ≥ 40 years (range40 – 87 years) were recruited from March 2008 to July 2017. The calibers of retinal microvessels were graded using retinal photography, and each participant's self-reported sedentary behavior and physical activity time were obtained through an extensive questionnaire. Physical activity was classified as high-intensity activity(running, swimming and basketball), moderate-intensity activity (Taichi, shuttlecock kicking and cycling)and low intensity activity (walking). Multivariate linear regression was used to explore the relationship between life activity habits and retinal microvessel caliber. Results: After exclusion of some recruited particpants for different reasons, 5 857 subjects were inclinded in the final analysis. After adjustment for age, gender,body mass index, blood pressure, fasting plasma glucose, triglycerides, total cholesterol, smoking status,and drinking status, the sedentary time was negatively associated with the caliber of the central retinal arterioles (β=-0.29, P =0.032). There was no significant association between physical activity and retinal vascular caliber. Conclusions: Sedentary time was significantly and independently associated with a decrease in the caliber of central retinal arterioles. The results suggest that sedentary behavior probably increases the risk of cardiovascular diseases among Chinese adults.
张雪平,廖炽媚,张威,黄红飞,何明光. 静坐和运动时间与视网膜血管管径的相关性[J]. 中华眼视光学与视觉科学杂志, 2017, 19(11): 650-655.
Xueping Zhang,Chimei Liao,Wei Zhang,Hongfei Huang,Mingguang He. Effects of sedentary behavior and physical activity on the caliber of retinal microvessels in Chinese adults. Chinese Journal of Optometry Ophthalmology and Visual science, 2017, 19(11): 650-655. DOI: 10.3760/cma.j.issn.1674-845X.2017.11.003
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