Objective: To report clinical observations of secondary corneal amyloidosis (SCA) related to trichiasis diagnosed and treated at Qingdao Eye Hospital. Methods: In this retrospective series of case study, medical records of 7 patients with trichiasis-related SCA from January 2014 to December 2015 were reviewed. Patient age, gender, history of disease, clinical manifestation, diagnosis methods, treatments, and histopathological results were analyzed. The depth of amyloid deposition in the corneal stroma was examined with optical coherence tomography (OCT) or ultrasound biomicroscopy (UBM). Results: The patients were 5 males and 2 females, age 11-86 years. All patients had a history of trichiasis. The common characteristics of the corneal lesions were a unilateral and well-circumscribed mass, with an irregular and mulberry-like surface, protuberant from the corneal surface at the position irritated by trichiasis. OCT or UBM showed Descemet's membrane was uninvolved in all cases. Lamellar keratoplasties were performed for 3 patients, and 1 patient underwent lesion excision combined with amniotic membrane covering. For the other 3 patients, the entropion and trichiasis were corrected with surgeries, but the mass was not resected because visual acuity was not obviously affected. Amorphous eosinophilic materials, with positive Congo red stain and apple-green birefringence beneath the epithelium were revealed by histopathology.Conclusions: SCA related to trichiasis typically presents a unilateral, well-circumscribed, irregular, and mulberry-like mass protuberant from the corneal surface at the position irritated by trichiasis.