光学相干断层扫描血管造影在青光眼中的应用

doi:10.3760/cma.j.issn.1674-845X.2019.07.013

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摘要光学相干断层扫描血管造影（OCTA）是一种全新的、非侵入性的成像系统,可产生视网膜、脉络膜层的结构数据,显示结构和血液流动信息。分频幅去相关血管成像（SSADA）算法（OCTA的一个重要组成部分）有助于降低信噪比,通过运动对比使视网膜血管成像更清晰,从而为治疗提供更加有意义的图像及数据,是眼科检测方法的一个重大突破。目前对于青光眼缺乏有效的早期诊断方法。OCTA的出现使得血流动力学可以作为评价青光眼的指标。现将对这项新的无创性检查方法在闭角型青光眼、开角型青光眼、正常眼压性青光眼这三种类型的青光眼临床上的应用进行综述。

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	叶鳞泓
	袁晴
	邵毅

关键词 ：光学相干断层扫描血管造影, 青光眼, 应用

Abstract：Optical coherence tomography angiography (OCTA) is a new, non-invasive imaging system, can produce the structure data of retina and choroid, shows the structure and blood flow information. Split-spectrum amplitude-decorrelation angiography (SSADA) algorithman (an important part of OCTA) can help reduce the signal-to-noise ratio, enhancing visualization of retinal vasculature using motion contrast. OCTA can provide more meaningful image data for the treatment which is a major breakthrough in the eye detection method. Currently there is lack of effective early diagnosis methods for glaucoma. OCTA as a parameter, can evaluate the structural parameters of glaucoma. This article will review the application of this new non-invasive method in the clinical application of three types of glaucoma: Angle-closure glaucoma, open angle glaucoma and normal tension glaucoma.

Key words： optical coherence tomography angiography glaucoma application

收稿日期: 2018-12-25

基金资助:国家自然科学基金（81160118、81460092、81400372、81660158）; 江西省远航工程项目（2014022）; 江西省自然科学基金重大项目（20161ACB21017）; 江西省自然科学基金（20151BAB215016）; 江西省科技支撑计划项目（20151BBG70223）

通讯作者: 邵毅（ORCID：0000-0003-1571-2433）,Email：freebee99@163.com

作者简介: 叶鳞泓（ORCID：0000-0001-5924-4016）,Email：1351363173@qq.com

引用本文:

叶鳞泓, 袁晴, 邵毅. 光学相干断层扫描血管造影在青光眼中的应用[J]. 中华眼视光学与视觉科学杂志, 2019, 21(7): 557-560. Linhong Ye, Qing Yuan, Yi Shao. The Application of Optical Coherence Tomography Angiography in Glaucoma. Chinese Journal of Optometry Ophthalmology and Visual science, 2019, 21(7): 557-560. DOI: 10.3760/cma.j.issn.1674-845X.2019.07.013

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https://www.cjoovs.com/CN/10.3760/cma.j.issn.1674-845X.2019.07.013 或 https://www.cjoovs.com/CN/Y2019/V21/I7/557

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