1 Department of Ophthalmology, The Second Xiangya Hospital of Central South University, Changsha 410011, China 2 Department of Ophthalmology, Hunan Province Children's Hospital, Changsha 410007, China 3 Hunan Clinical Research Center for Ocular Surface Diseases, Changsha Aier Eye Hospital, Changsha 410015, China
Abstract：Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase, widely distributed in the cytoplasm of cells in the body. It can transmit signals from cell membrane receptors and intercellular growth factors, and participate in the regulation of cell growth and differentiation, adhesion and migration, proliferation and apoptosis, and other important biological processes. FAK is at the intersection of many signal transduction pathways in cells, and researchers have confirmed that it plays an important role in many systemic diseases. This review summarizes the general characteristics of FAK and its functions in ophthalmic diseases.
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