OCTA在评估高度近视眼底形态及血流变化中应用的研究进展

doi:10.3760/cma.j.cn115909-20200420-00157

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摘要近视是世界范围内发病率最高的眼部疾病，且发病原因尚不明确，是全球关注的公共卫生问题。高度近视眼及其眼底并发症严重影响视功能。光学相干断层扫描血管成像（OCTA）技术是一种对视网膜、脉络膜自动精确分层，通过量化血流面积、无血流面积和血流密度区域，对视网膜、脉络膜多层面进行定性、定量的研究手段。应用OCTA，可对高度近视眼的发病机制从视网膜各层次微血管层面进行深入研究。笔者就高度近视眼底形态改变以及OCTA在评估高度近视眼底结构、功能及血流密度变化中的应用进行综述，期望为高度近视发病机制探究及干预提供指导。

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关键词 ： , 高度近视, 光学相干断层扫描血管成像, 视网膜神经纤维层, 视网膜血流密度, 脉络膜血流密度

Abstract： Myopia, a leading cause of blindness, and the pathogenesis is unclear, is considered to be a public health problem worldwide. High myopia and its fundus complications seriously impair visual function. Optical coherence tomography angiography (OCTA) is an automatic and accurate delamination of the retina and choroid, which can qualitatively and quantitatively detect the retina and choroid by quantifying the microvasculature area. OCTA can be used to detect the pathogenesis of high myopia at the microvascular level of the retina. This review summarizes the morphological changes of the fundus in high myopia and the application of OCTA in evaluating the changes in fundus structure, function and microvasculature density in high myopia.

Key words： high myopia optical coherence tomography angiography retinal nerve fiber layer retinal microvasculature density choroidal microvasculature density

收稿日期: 2020-04-20

PACS:

基金资助: 国家自然科学基金面上项目（81670859，81970801）；湖南省自然科学基金（2019JJ40001）；长沙市科技局重点研发项目（kh1801229）；爱尔眼科医院集团科研基金研究所立项项目（AR1906D1，AM1906D2）

通讯作者: 段宣初（ORCID：0000-0003-1101-0602），Email：duanxchu@126.com

引用本文:

罗金香1，2 肖满意1 段宣初1，2，3. OCTA在评估高度近视眼底形态及血流变化中应用的研究进展[J]. 中华眼视光学与视觉科学杂志, 2020, 22(10): 789-795. Jinxiang Luo1, 2, Manyi Xiao1,Xuanchu Duan1, 2, 3. Progress of Application of OCTA in Evaluating Fundus Morphology and Microvasculature Changes in High Myopia. Chinese Journal of Optometry Ophthalmology and Visual science, 2020, 22(10): 789-795. DOI: 10.3760/cma.j.cn115909-20200420-00157

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https://www.cjoovs.com/CN/10.3760/cma.j.cn115909-20200420-00157 或 https://www.cjoovs.com/CN/Y2020/V22/I10/789

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