Abstract： Objective: To study the primary clinical effects that occur with fenestration membranectomy to produce an opening through the fibrous membrane closure of the continuous curvilinear capsulorrhexis (CCC) after cataract surgery. Methods: This was a restrospective study. Fifteen patients (15 eyes) had surgical CCC openings that were completely closed by a fibrous membrane after cataract surgery. They underwent fenestration with membranectomy in the Taizhou Eye Hospital between September 2011 and September 2018. The causes of fibrous membrane closure, surgical methodology and its effectiveness are also discussed. Results: Visual acuity improved significantly postoperative. Among them the uncorrected visual acuity (UCVA) was 0.2-0.3 in 4 eyes, 0.4-0.5 in 8 eyes and 0.6-0.7 in 3 eyes the next day after operation. The interior of the fenestration opening of the anterior capsule was transparent, the size of the fenestration opening was about 4.5 mm×5.0 mm, the intraocular lens (IOL) position was normal without displacement, and the optical part of IOL was flattened in all eyes postoperatively. None of the patients had major complaints about glare. Conclusions: The causes of fibrous membrane closure of the CCC opening may be related to the proliferation and migration of lens epithelial cells and fibroblasts after cataract surgery. The fibrous membrane closure of the CCC opening can be effectively solved by fenestration of the membrane and can significantly improve visual acuity
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