Abstract： Virtual reality (VR) is a hot-button technology topic well known to many research communities. Its technical progress is set to prompt advances in modern ophthalmology research. At present, many studies have shown VR has practical value for ophthalmologist training and eye disease research. This paper presents a systematic review of specific applications of VR in various fields of ophthalmology, analyzes the connection between VR and ophthalmology, and briefly summarizes the future direction of VR use in ophthalmology based on current results.
彭振 吴呈润 张旭. 虚拟现实技术在眼科领域的应用现状及研究进展[J]. 中华眼视光学与视觉科学杂志, 2021, 23(8): 631-635.
Zhen Peng, Chengrun Wu, Xu Zhang. Current State and Progress of Research on Virtual Reality Technology and Its Application for Ophthalmology. Chinese Journal of Optometry Ophthalmology and Visual science, 2021, 23(8): 631-635. DOI: 10.3760/cma.j.cn115909-20200728-00313
Mahmood T, Scaffidi MA, Khan R, et al. Virtual reality simulation in endoscopy training: Current evidence and future directions. World J Gastroenterol, 2018, 24(48): 5439-5445. DOI: 10.3748/wjg.v24.i48.5439.
[3]
BozkurtOflaz A, EkinciKöktekir B, Okudan S. Does cataract surgery simulation correlate with real-life experience? Turk J Ophthalmol, 2018, 48(3): 122-126. DOI: 10.4274/tjo.10586.
[4]
Jacobsen MF, Konge L, Bach-Holm D, et al. Correlation of virtual reality performance with real-life cataract surgery performance. J Cataract Refract Surg, 2019, 45(9): 1246-1251. DOI: 10.1016/j.jcrs.2019.04.007.
[5]
Ferris JD, Donachie PH, Johnston RL, et al. Royal College of Ophthalmologists' National Ophthalmology Database study of cataract surgery: report 6. The impact of EyeSi virtual reality training on complications rates of cataract surgery performed by first and second year trainees. Br J Ophthalmol, 2020, 104(3): 324-329. DOI: 10.1136/bjophthalmol-2018-313817.
[6]
Selvander M, Asman P. Virtual reality cataract surgery training: learning curves and concurrent validity. Acta Ophthalmol, 2012, 90(5): 412-417. DOI: 10.1111/j.1755-3768.2010.02028.x.
[7]
Ng DS, Sun Z, Young AL, et al. Impact of virtual reality simulation on learning barriers of phacoemulsification perceived by residents. Clin Ophthalmol, 2018, 12: 885-893. DOI: 10.2147/opth.S140411.
[8]
McCannel CA. Continuous Curvilinear Capsulorhexis Training and Non-Rhexis Related Vitreous Loss: The Specificity of Virtual Reality Simulator Surgical Training (An American Ophthalmological Society Thesis). Trans Am Ophthalmol Soc, 2017, 22; 115: T2.
[9]
laCour M, Thomsen A, Alberti M, et al. Simulators in the training of surgeons: is it worth the investment in money and time? 2018 Jules Gonin lecture of the Retina Research Foundation. Graefes Arch Clin Exp Ophthalmol, 2019, 257(5): 877-881. DOI: 10.1007/s00417-019-04244-y.
[10]
Selvander M, Asman P. Ready for OR or not? Human reader supplements Eyesi scoring in cataract surgical skills assessment. Clin Ophthalmol, 2013, 7: 1973-1977. DOI: 10.2147/opth. S48374.
[11]
Goh R, Kong Y, McAlinden C, et al. Objective assessment of activity limitation in glaucoma with smartphone virtual reality goggles: A Pilot Study. Transl Vis Sci Technol, 2018, 7(1): 10. DOI: 10.1167/tvst.7.1.10.
[12]
Jones PR, Somoskeöy T, Chow-Wing-Bom H, et al. Seeing other perspectives: Evaluating the use of virtual and augmented reality to simulate visual impairments (OpenVisSim). NPJ Digit Med, 2020, 3: 32. DOI: 10.1038/s41746-020-0242-6.
[13]
Daga FB, Macagno E, Stevenson C, et al. Wayfinding and glaucoma: A Virtual Reality Experiment. Invest Ophthalmol Vis Sci, 2017, 58(9): 3343-3349. DOI: 10.1167/iovs.17-21849.
[14]
Diniz-Filho A, Boer ER, Gracitelli CP, et al. Evaluation of Postural Control in Patients with Glaucoma Using a Virtual Reality Environment. Ophthalmology, 2015, 122(6): 1131-1138. DOI: 10.1016/j.ophtha.2015.02.010.
[15]
Sayed AM, Kashem R, Abdel-Mottaleb M, et al. Toward improving the mobility of patients with peripheral visual field defects with novel digital spectacles. Am J Ophthalmol, 2020, 210: 136-145. DOI: 10.1016/j.ajo.2019.10.005.
[16]
Li B, Chu H, Yan L, et al. Individualized visual reality training improves visual acuity and visual field defects in patients with glaucoma: A Preliminary Study Report. Cyberpsychol Behav Soc Netw, 2020, 23(3): 179-184. DOI: 10.1089/ cyber.2020.0083.
[17]
You QS, Wu LJ, Duan JL, et al. Prevalence of myopia in school children in greater Beijing: The Beijing Childhood Eye Study. Acta Ophthalmol, 2014, 92(5): 398-406. DOI: 10.1111/ aos.12299.
[18]
Maiello G, Kerber KL, Thorn F, et al. Vergence driven accommodation with simulated disparity in myopia and emmetropia. Exp Eye Res, 2018, 166: 96-105. DOI: 10.1016/ j.exer.2017.10.004.
[19]
Turnbull PRK, Phillips JR. Ocular effects of virtual reality headset wear in young adults. Sci Rep, 2017, 7(1): 16172. DOI: 10.1038/s41598-017-16320-6.
[20]
Guggenheim JA, Northstone K, McMahon G, et al. Time outdoors and physical activity as predictors of incident myopia in childhood: A prospective cohort study. Invest Ophthalmol Vis Sci, 2012, 53(6): 2856-2865. DOI: 10.1167/iovs.11-9091.
[21]
Zhao F, Chen L, Ma H, et al. Virtual reality: A possible approach to myopia prevention and control? Med Hypotheses, 2018, 121: 1-3. DOI: 10.1016/j.mehy.2018.09.021.
Herbison N, MacKeith D, Vivian A, et al. Randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the I-BiT system. Br J Ophthalmol, 2016, 100(11): 1511-1516. DOI: 10.1136/ bjophthalmol-2015-307798.
[24]
Li X, Yang C, Zhang G, et al. Intermittent exotropia treatment with dichoptic visual training using a unique virtual reality platform. Cyberpsychol Behav Soc Netw, 2019, 22(1): 22-30.
DOI: 10.1089/cyber.2018.0259.
[25]
?iak P, Holm A, Hali?ka J, et al. Amblyopia treatment of adults with dichoptic training using the virtual reality oculus rift head mounted display: preliminary results. BMC Ophthalmol, 2017, 17(1): 105. DOI: 10.1186/s12886-017-0501-8.
[26]
Padmanaban N, Konrad R, Stramer T, et al. Optimizing virtual reality for all users through gaze-contingent and adaptive focus displays. Proc Natl Acad Sci USA, 2017, 114(9): 2183-2188. DOI: 10.1073/pnas.1617251114.
[27]
Nesaratnam N, Thomas P, Vivian A. Stepping into the virtual unknown: feasibility study of a virtual reality-based test of ocular misalignment. Eye (Lond), 2017, 31(10): 1503-1506. DOI: 10.1038/eye.2017.97.
[28]
Miao Y, Jeon JY, Park G, et al. Virtual reality-based measurement of ocular deviation in strabismus. Comput Methods Programs Biomed, 2020, 185: 105132. DOI: 10.1016/ j.cmpb.2019.105132.
[29]
Tsapakis S, Papaconstantinou D, Diagourtas A, et al. Visual field examination method using virtual reality glasses compared with the Humphrey perimeter. ClinOphthalmol, 2017, 11: 1431-1443. DOI: 10.2147/OPTH.S131160.
[30]
Versek C, Rissmiller A, Tran A, et al. Portable system for neurooptical diagnostics using virtual reality display. Mil Med, 2019, 184(Suppl 1): 584-592. DOI: 10.1093/milmed/usy286.
[31]
Xu L, Huang M, Lan J, et al. Assessment of binocular imbalance with an augmented virtual reality platform in a normal population. Cyberpsychol Behav Soc Netw, 2019, 22(2): 127- 131. DOI: 10.1089/cyber.2019.0020.
[32]
Maloca PM, de Carvalho J, Heeren T, et al. High-performance virtual reality volume rendering of original optical coherence tomography point-cloud data enhanced with real-time ray casting. Transl Vis Sci Technol, 2018, 7(4): 2. DOI: 10.1167/ tvst.7.4.2.
[33]
Draelos M, Keller B, Viehland C, et al. Real-time visualization and interaction with static and live optical coherence tomography volumes in immersive virtual reality. Biomed Opt Express, 2018, 9(6): 2825-2843. DOI: 10.1364/boe.9.002825.
[34]
Gallagher K, Jain S, Okhravi N. Making and viewing stereoscopic surgical videos with smartphones and virtual reality headset. Eye (Lond), 2016, 30(4): 503-504. DOI: 10.1038/ eye.2015.282.
[35]
Ho DK. Using smartphone-delivered stereoscopic vision in microsurgery: a feasibility study. Eye (Lond), 2019, 33(6): 953- 956. DOI: 10.1038/s41433-019-0356-8.
[36]
Khelemsky R, Hill B, Buchbinder D. Validation of a Novel Cognitive Simulator for Orbital Floor Reconstruction. J Oral Maxillofac Surg, 2017, 75(4): 775-785. DOI: 10.1016/ j.joms.2016.11.027.
[37]
Dyer E, Swartzlander BJ, Gugliucci MR. Using virtual reality in medical education to teach empathy. J Med Libr Assoc, 2018, 106(4): 498-500. DOI: 10.5195/jmla.2018.518.
[38]
Zhang JF, Paciorkowski AR, Craig PA, et al. Bio VR: a platform for virtual reality assisted biological data integration and visualization. BMC Bioinformatics, 2019, 20(1): 78. DOI: 10.1186/s12859-019-2666-z.
[39]
Wang Y, Li Q, Liu L, et al. TeraVR empowers precise reconstruction of complete 3-D neuronal morphology in the whole brain. Nat Commun, 2019, 10(1): 3474. DOI: 10.1038/ s41467-019-11443-y.
[40]
Parker AJ. Vision in our three-dimensional world. Philos Trans R SocLond B Biol Sci, 2016, 371(1697): 20150251. DOI: 10.1098/rstb.2015.0251.
[41]
Lui JT, Compton ED, Ryu WHA, et al. Assessing the role of virtual reality training in Canadian Otolaryngology-Head & Neck Residency Programs: a national survey of program directors and residents. J Otolaryngol Head Neck Surg, 2018, 47(1): 61. DOI: 10.1186/s40463-018-0309-4.
[42]
Paul SK, Clark MA, Scott IU, et al. Virtual eye surgery training in ophthalmic graduate medical education. Can J Ophthalmol, 2018, 53(6): e218-e220. DOI: 10.1016/j.jcjo.2018.03.018.
[43]
Kim HK, Park J, Choi Y, et al. Virtual reality sickness questionnaire (VRSQ): Motion sickness measurement index in a virtual reality environment. Appl Ergon, 2018, 69: 66-73. DOI: 10.1016/j.apergo.2017.12.016.
[44]
Yu M, Zhou R, Wang H, et al. An evaluation for VR glasses system user experience: The influence factors of interactive operation and motion sickness. Appl Ergon, 2019, 74: 206-213. DOI: 10.1016/j.apergo.2018.08.012.
[45]
Bergeron M, Lortie CL, Guitton MJ. Use of virtual reality tools for vestibular disorders rehabilitation: A Comprehensive Analysis. Adv Med, 2015, 2015: 916735. DOI: 10.1155/2015/916735.
[46]
Fajnerová I, Greguš D, Hlinka J, et al. Could prolonged usage of GPS navigation implemented in augmented reality smart glasses affect hippocampal functional connectivity?. Biomed Res Int, 2018, 2018: 2716134. DOI: 10.1155/2018/2716134.
[47]
Tychsen L, Thio LL. Concern of photosensitive seizures Evoked by 3D video displays or virtual reality headsets in children: Current Perspective. Eye Brain, 2020, 12: 45-48. DOI: 10.2147/ EB.S233195.
浙公网安备 33030202001892号