1 Department of Ophthalmology, People's Hospital of Changsha County, Hunan Provincial People's Hospital Xingsha Branch, Changsha 410100, China 2 Center of Ophthalmology and Optometric, Hunan Provincial People's Hospital, the First Affiliated Hospital of Hunan Normal University, Changsha 410000, China
Abstract:Objective: To evaluate the reference value of selecting implantable collamer lens (ICL) size by Sirius anterior segment analysis system. Methods: We retrospectively collected 146 eyes of 73 patients with high myopia who underwent ICL implantation in Hunan Provincial People's Hospital from January 2016 to August 2017. All ICL diameters were selected by the anterior segment indicators such as horizontal visible iris diameter (HVID), horizontal anterior chamber diameter (HACD), anterior chamber depth (ACD), which was measured by Sirius anterior segment analysis system. ICL calculation software provided by STAAR company is used to select ICL diameter based on these indicators. All patients were followed 3 months to 1 year. The data before and after surgery were analyzed using Friedman M test, repeated measures ANOVA, paired t test and multiple linear regression equation. Results: The postoperative uncorrected distance visual acuity (UDVA) of all patients was improved compare with preoperative value (χ2 =156.08, P<0.001). The effective index and safety index were greater than 1 at each postoperative period. There was no significant difference in intraocular pressure (IOP) during the preoperative and postoperative follow-up (P=0.054). The endothelial cell density (ECD), anterior chamber depth (ACD) and anterior chamber angle (ACA) were decreased after surgery (t=4.63, 31.17, 23.57, all P<0.001). The postoperative mean vault was (483±231) μm and the ideal vault eyes accounted for 83.6%. ICL diameter (mm)=6.474+0.43×HVID (mm) +0.299×ACD (mm) (R2 =0.44, F=36.23, P<0.001). No complications such as cataract, goniosynechia and glaucoma occurred in all patients. Conclusions: The ICL selected by Sirius anterior segment analysis system is safe and effective in the treatment of high myopia; the HVID, HACD, and ACD obtained by Sirius can be used as important parameters for ICL diameter selection.
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