CASIA2与IOLMaster 700测量眼前段参数的比较

doi:10.3760/cma.j.cn115909-20220330-00117

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摘要目的：比较新型扫频源眼前节相干光层析成像仪CASIA2与扫频源光相干生物测量仪IOLMaster700 测量眼前段结构参数的差异性和一致性。方法：回顾性研究。选取2020年4—5月在天津医科大学眼科医院就诊的白内障患者95例（95眼），分别采用CASIA2和IOLMaster700测量中央角膜厚度（CCT）、前房深度（ACD）、晶状体厚度（LT）、角膜曲率陡峭轴（Ks）、角膜曲率平坦轴（Kf）。采用配对样本t检验比较2种仪器对CCT、ACD、LT、Ks、Kf测量结果的差异性；采用Pearson检验分析各参数测量结果在2种仪器间的相关性；采用Bland-Altman法评价各参数测量结果在2种仪器之间的一致性。结果：CASIA2和IOLMaster700测量CCT、ACD、LT差异均有统计学意义（t=-11.94，P<0.001；t=8.52，P<0.001；t=-2.97，P=0.004）；测量Ks、Kf差异无统计学意义；2种仪器间测量的CCT、ACD、LT、Ks、Kf均呈正相关（r=0.99、0.99、0.99、0.98、0.97，均P<0.001）。Bland-Altman一致性分析显示，2种仪器测量CCT、ACD、LT差值的均数分别为-7.516μm、0.043mm、0.023mm，95%一致性界限（LoA）分别为（-19.92，4.48）μm、（-0.055，0.139）mm、（-0.120，0.160）mm。2种仪器测量Ks、Kf差值的均数为0.028D、0.061D，95%LoA分别为（-0.65，0.77）D、（-0.52，0.58）D；在95%LoA外分别占了7.36%（7/95）、6.31%（6/95），一致性较差。结论：CASIA2和IOLMaster700的眼前节参数测量结果存在一定差异，且一致性欠佳。

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关键词 ：眼前段参数, CASIA2, IOLMaster700, 白内障

Abstract：Objective: To evaluate the difference and the consistency of the ocular anterior segment parameters measured with CASIA 2 and IOLMaster 700 in patients with cataract. Methods: In this retrospective study, 95 eyes of 95 patients underwent pre-operative examination for cataract surgery from April 2020 to May 2020 were involved. The central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), keratometry of the steepest meridian (Ks) and keratometry of the flattest meridian (Kf) measured by CASIA 2 and IOLMaster 700 were documented and analyzed using paired t test for differences, earson's test for correlation and Bland-Altman test for consistency. Results: The differences of CCT, ACD and LT values measured by CASIA 2 and IOLMaster 700 were statistically significant (t=-11.94, P<0.001; t=8.52, P<0.001, t=-2.97, P=0.004, respectively), while the differences of Ks and Kf were not statistically significant. The CCT, ACD, LT, Ks and Kf values measured with two instruments were significantly correlated (r=0.99, 0.99, 0.99, 0.98 and 0.97, all P<0.001). Bland-Altman analysis showed that the mean differences of CCT, ACD and LT were -7.516 μm、0.043 mm、0.023 mm, respectively. The limits of agreement (LoA) were -19.92, 4.48 μm, -0.055, 0.139 mm, -0.120, 0.160 mm.The mean differences of Ks and Kf from the two instruments were 0.028 D and 0.061 D, respectively. The 95% LoA were -0.65, 0.77 D and -0.52, 0.578 D. The proportion outside 95% LoA were 7.36%(7/95) and 6.31% (6/95). The values of CCT, ACD, LT, Ks and Kf measured by the two instruments were not consistent.Conclusion: The CCT, ACD, LT, Ks and Kf measured with CASIA 2 and IOLMaster 700 were not consistent.

Key words： anterior segment parameters CASIA 2 IOLMaster 700 cataract

收稿日期: 2022-03-30

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通讯作者: 林松（ORCID：0000-0001-6535-4297），Email：linsong123123@sina.com

引用本文:

王抒阳,步绍翀,蒋元丰,等. CASIA2与IOLMaster 700测量眼前段参数的比较[J]. 中华眼视光学与视觉科学杂志, 2022, 24(11): 867-872. Shuyang Wang, Shaochong Bu, Yuanfeng Jiang,et al. Comparison of CASIA 2 and IOLMaster 700 for Measuring the Anterior Segment Data. Chinese Journal of Optometry Ophthalmology and Visual science, 2022, 24(11): 867-872. DOI: 10.3760/cma.j.cn115909-20220330-00117

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https://www.cjoovs.com/CN/10.3760/cma.j.cn115909-20220330-00117 或 https://www.cjoovs.com/CN/Y2022/V24/I11/867