Abstract:Objective: To investigate the distribution characteristics of corneal power of 2 mm, 4 mm and 6 mm diameter zones centered on the pupil and age-related change in cornea. Methods: In this retrospective serial case study, a total of 254 eyes were included by randomly, which were divided into three groups by age, including 20-39 age group (Group A, 102 eyes), 40-59 age group (Group B, 73 eyes) and ≥60 age group (Group C, 79 eyes). Simulated keratometry (Simk), total corneal refractive power (TCRP) were evaluated.Analysis of Variance was used for comparing the difference between Simk and TCRP. Evaluating uniformity of Simk and TCRP was based on Bland-Altman plot. Regression analysis was used for the age-related trend of Simk and TCRP. Paired-samples ttest was used to compare the difference between Simk and TCRP in 2, 4 and 6 mm. Results:The Simk and TCRP of 2, 4 mm diameter zones centered on the pupilwere signifcant differences between them (t=6.30, P=0.002;t=4.44, P=0.001); However, The Simk and TCRPof 6 mm diameter zones centered on the pupil were no statistically signifcant differences between them (P>0.05). In 2 mm diameter zones centered on the pupil, there were statistically signifcant differences between three groups (F=4.66,P=0.010;F=3.87,P=0.022),Among them, groupA was significant different from B and C (P<0.05). In 4 mm diameter zones centered on the pupil,there were statistically significant differences between three groups (F=6.85,P=0.001;F=6.07,P=0.003). Among them, group Awas signifcant different from B and C (P<0.05). In 6 mm diameter zones centered on the pupil, there were statistically significant differences between three groups (F=9.91, P<0.001; F=10.15,P<0.001), both Simk and TCRPof Agroup in all corneal diameter zones showed statistically signifcant differences with B, C group respectively (P<0.001). Conclusion: Simk and TCRP centered on pupil and the age-related change in corneal should be taken seriously in corneal refractive surgery and cataract surgery. Simk and TCRP shows steeper with aging, which may tend to be stable after 40 years old.
王忠叶,刘秀花,张敏,等. 角膜曲率区域分布及随年龄变化趋势分析[J]. 中华眼视光学与视觉科学杂志, 2023, 25(1): 44-49.
Zhongye Wang1, Xiuhua Liu2, Min Zhang2, et al. Research of Corneal Power Distribution andAge-Related Change in Cornea. Chinese Journal of Optometry Ophthalmology and Visual science, 2023, 25(1): 44-49. DOI: 10.3760/cma.j.cn115909-20210930-00403