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Study of the Curative Effect of Two Different Suture Methods in the Treatment of Pterygium |
Daikun Lei, Xiaoyun Dong, Xia Li, Yi Liu, Ying Zhou, Peng Li |
Department of Ophthalmology, Beijing Road Medical District, General Hospital of Xinjiang Military Region, 474 Hospital of the People's Liberation Army, Urumqi 830013, China |
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Abstract Objective: To study the clinical effect of two different suture methods in the treatment of primary pterygium. Methods: This was a prospective study of 128 patients (128 eyes) with pterygium who were hospitalized and underwent surgery in the 474 Hospital of the People's Liberation Army from April 2015 to April 2018. Patients were randomly divided into two groups: The experimental group and the control group. The experimental group was treated with pterygium resection combined with a continuous suture of autograft conjunctival flap, while the control group was treated with pterygium resection combined with an intermittent suture of autograft conjunctival flap. Pain and corneal irritation in the two groups were monitored on the 1st, 3rd and 7th day after the operation. The amount of time for the corneal epithelium to heal completely was determined by corneal fluorescence staining. The complete healing of the conjunctiva, scar fiber hyperplasia and pterygium recurrence were recorded during a 6-month followup period. An independent samples t test was used to compare the indexes between the two groups; a Chisquare test was used to compare the rates between the two groups (direct calculation of the P value with the aid of an accurate probability method if necessary). Results: Scores for pain and corneal stimulation symptoms in the experimental group were lower than for those in the control group on the 1st and 3rd day after the operation (scores for pain: t=-40.477, P<0.001; t=-23.376, P<0.001; scores for corneal stimulation symptoms: t=-18.431, P<0.001; t=-7.894, P<0.001). Comparisons were made preoperatively and on the 7th day after the operation. There was no significant difference between the two groups. Corneal fluorescence staining 7 days after the operation showed that the experimental group had a higher complete healing rate for the corneal epithelium than the control group (χ2 =4.354, P=0.037; χ2 =13.333, P<0.001). There was no significant difference between the two groups. The healing rate of the experimental group was higher than that for the control group (χ2 =8.848, P=0.003), but the scar healing rate of the experimental group was slower than that of the control group (χ2 =8.214, P=0.004). There was no significant difference in the recurrence rate of pterygium between the two groups. Sutures were removed sooner in the experimental group than in the control group (t=-32.686, P<0.001). The pain score of the experimental group was lower than that of the control group (t=-26.580, P<0.001). Conclusion: For pterygium excision combined with continuous suture and conjunctival flap autograft for the treatment of primary pterygium, postoperative eye pain, irritation and inflammatory reaction are slight, corneal epithelial healing is faster, scar formation can be significantly reduced, postoperative suture removal is earlier, time is shorter and pain is slighter.
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Received: 24 December 2019
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Fund:Xinjiang Uygur Autonomous Region Health Committee Technology Promotion Project (SYTG-201993) |
Corresponding Authors:
Peng Li, Department of Ophthalmology, Beijing Road Medical District, General Hospital of Xinjiang Military Region, 474 Hospital of the People's Liberation Army, Urumqi 830013, China (Email: freemanlp00@sina.com)
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