小鼠肌节同源盒基因同系物2条件性敲除在先天性白内障发生中的作用
The Effects of msh Homeobox 2 Conditional Knockout on Congenital Cataract Formation in Mice
Ziyan Yu, Wenting Yu, Jia Liu, Xinwei Wu, Jiangyue Zhao, Jinsong Zhang
小鼠肌节同源盒基因同系物2条件性敲除在先天性白内障发生中的作用 |
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于紫燕, 于雯婷, 刘佳, 吴欣蔚, 赵江月, 张劲松 |
The Effects of msh Homeobox 2 Conditional Knockout on Congenital Cataract Formation in Mice |
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Ziyan Yu, Wenting Yu, Jia Liu, Xinwei Wu, Jiangyue Zhao, Jinsong Zhang
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| 2月龄Msx2CKO与Msx2WT小鼠眼部表型 A:58.3% Msx2CKO 2月龄成鼠眼部表现为角膜轻微混浊,晶状体变小,可以观察到晶状体核性混浊,小眼球畸形;B:Msx2WT小鼠2月龄成鼠表型,没有发生白内障;C和D:解剖小鼠的眼球,取出晶状体,观察到Msx2CKO小鼠晶状体核性混浊,且体积明显小于Msx2WT小鼠。标尺:1 cm |
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