Outcome for Different Treatments of Traumatic Endophthalmitis
Ruixin Gao,Tingting Cao,Guoxin Bai,Yu Liu
Department of Ophthalmology, Cangzhou Municipal Central Hospital, Cangzhou 061000, China Administration Department, Cangzhou Municipal Central Hospital, Cangzhou, 061000, China
Objective: To assess the effectiveness of the different clinical treatments of traumatic endophthalmitis.Methods: This retrospective study included one eye of 73 patients diagnosed with traumatic endophthalmitis from November 2010 to July 2016 at Cangzhou Municipal Central Hospital. Forty-one patients were treated by vitrectomy and 32 immediately received intravitreal injection. For vitrectomy patients, 21 eyes received silicon oil tamponade, 9 eyes received C3F8 tamonade, and 11 eyes received
no tamponade. At the beginning of each vitrectomy, vitreous purulence was extracted for bacterial and fungal culture and for drug sensitivity. Results: During the following 6-24 months, two victrectomized eyes with silicon oil tamponade and one eye with intravitreal injection atrophied. Endophthalmitis was controlled for the remaining 70 eyes. Sixty-three strains of organisms were isolated from 58 eyes with traumatic endophthalmitis, including five eyes with polymicrobial infection. Among them, 39(62%)
were gram-positive, 13(21%) were fungi, and 11(18%) were gram-negative bacteria. The most common organisms were Staphylococcus epidermidis at 25% of the eyes, Aspergillus at 14%, and Staphylococcus aureus at 11%. Conclusions: For traumatic endophthalmitis, once confirmed, actions should be undertaken immediately. Vitrectomy and antimicrobials are both effective treatments.
Kleinberg TT, Tzekov RT, Stein L, et al. Vitreous substitutes: A comprehensive review. Surv Ophthalmol, 2011, 56(4): 300-323.DOI: 10.1016/j.survophthal.2010.09.001.
[8]
Ornek N, Apan T, O?urel R, et al. Comparison of the antimicrobial effect of heavy silicone oil and conventional silicone oil against endophthalmitis-causing agents. Indian
Gokce G, Sobaci G, Ozgonul C. Post-traumatic endophthalmitis: A mini-review. Semin Ophthalmol, 2015, 30(5-6): 470-474. DOI:10.3109/08820538.2013.877939.
[8]
Ornek N, Apan T, O?urel R, et al. Comparison of the antimicrobial effect of heavy silicone oil and conventional silicone oil against endophthalmitis-causing agents. Indian
Gokce G, Sobaci G, Ozgonul C. Post-traumatic endophthalmitis: A mini-review. Semin Ophthalmol, 2015, 30(5-6): 470-474. DOI:10.3109/08820538.2013.877939.
[10]
Garner WH, Scheib S, Berkowitz BA, et al. The effect of partial vitrectomy on blood-ocular barrier function in the rabbit. Curr Eye Res, 2001, 23(5): 372-381.
[11]
Zhang Y, Zhang M, Jiang C, et al. Intraocular foreign bodies in china: clinical characteristics, prognostic factors, and visual outcomes in 1, 421 eyes. Am J Ophthalmol, 2011, 152(1): 66-73.e1. DOI: 10.1016/j.ajo.2011.01.014.
Garner WH, Scheib S, Berkowitz BA, et al. The effect of partial vitrectomy on blood-ocular barrier function in the rabbit. Curr Eye Res, 2001, 23(5): 372-381.
[11]
Zhang Y, Zhang M, Jiang C, et al. Intraocular foreign bodies in china: clinical characteristics, prognostic factors, and visual outcomes in 1, 421 eyes. Am J Ophthalmol, 2011, 152(1): 66-73.e1. DOI: 10.1016/j.ajo.2011.01.014.
Long C, Liu B, Xu C, et al. Causative organisms of post-traumatic endophthalmitis: a 20-year retrospective study. BMC Ophthalmol,2014, 14: 34. DOI: 10.1186/1471-2415-14-34.
[13]
Pandita A, Merriman M. Ocular trauma epidemiology: 10-year retrospective study. N Z Med J, 2012, 125(1348): 61-69.
Long C, Liu B, Xu C, et al. Causative organisms of post-traumatic endophthalmitis: a 20-year retrospective study. BMC Ophthalmol,2014, 14: 34. DOI: 10.1186/1471-2415-14-34.