Department of Ophthalmology, Shanghai Pudong Hospital, Fudan University, Pudong Medical Center,Shanghai 201399, China
Shanghai Aier Eye Hospital, Shanghai 200336, China
Department of Ophthalmology, Eye & Ent Hospital of Fudan University, Shanghai 200031, China
Center for Medical Research and Innovation, Shanghai Pudong Hospital, Fudan University, Pudong Medical Center, Shanghai 201399, China
Objective: To analyze the ocular surface status in meibomian gland dysfunction patients after cataract surgery. Methods: This was a prospective study. We studied 83 eyes of 67 meibomian gland dysfunction patients who were treated in the Ophthalmology Department of Shanghai Pudong Hospital from January 2015 to January 2017 underwent phacoemulsification and intraocular lens implantation were studied and analyzed preoperatively and at 1 month, 2 months and 3 months postoperatively. Ocular symptom scores, lid margin abnormalities, corneal fluorescein staining (CFS), tear film breakup time (BUT),Schirmer Ⅰ test (SⅠT), and lower tear meniscus height, depth, and area using Fourier domain optical coherence omography were measured. Statistical methods are repeated measures of variance analysis. Results: The ocular symptom scores were worse at 1 month, 2 months and 3 months postoperatively (F=1193.031,P<0.001). BUT decreased postoperatively (F=21.042, P<0.001). However, lid margin abnormalities,CFS, lower tear meniscus (height, depth and area) and the SⅠT did not change significantly postoperatively.Conclusions: A worsening of ocular symptoms may occur without accompanying obvious structural changes in meibomian gland dysfunction patients after cataract surgery.
Methodologies to diagnose and monitor dry eye disease:report of the Diagnostic Methodology Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf, 2007, 5(2):
[1]
Tomlinson A, Bron AJ, Krob DR, et al. The international workshop on meibomian gland dysfunction: Report of the dignosis subcommittee. Invest Ophthalmol Vis Sci, 2011, 52(4):
20
06-2049. DOI: 10.1167/iovs.10-6997f.
[2]
Nichols KK, Foulks GN, Bron AJ, et al. The international workshop on meibomian gland dysfunction: executive summary.Invest Ophthalmol Vis Sci, 2011, 52(4): 1922-1929. DOI:
10
8-152.
[4]
Miller KL, Walt JG, Mink DR, et al. Minimal clinically important difference for the ocular surface disease index.Arch Ophthalmol, 2010, 128(1): 94-101. DOI: 10.1001/
10
1167/iovs.10-6997a.
archophthalmol.2009.356.
[5]
Schaumberg DA, Nichols JJ, Papas EB, et al. The international workshop on meibomian gland dysfunction: report of the subcommittee on the epidemiology of, and associated risk factors for, MGD. Invest Ophthalmol Vis Sci, 2011, 52(4): 1994-2005. DOI: 10.1167/iovs.10-6997e.
[6]
Han KE, Yoon SC, Ahn JM, et al. Evaluation of dry eye and meibomian gland dysfunction after cataract surgery. Am J Ophthalmol, 2014, 157(6): 1144-1150.e1. DOI: 10.1016/j.ajo.
[3]
Methodologies to diagnose and monitor dry eye disease:report of the Diagnostic Methodology Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf, 2007, 5(2):
Miller KL, Walt JG, Mink DR, et al. Minimal clinically important difference for the ocular surface disease index.Arch Ophthalmol, 2010, 128(1): 94-101. DOI: 10.1001/
Savini G, Goto E, Carbonelli M, et al. Agreement between stratus and visante optical coherence tomography systems in tear meniscus measurements. Cornea, 2009, 28(2): 148-151. DOI:10.1097/ICO.0b013e31818526d0.
[11]
Ibrahim OM, Dogru M, Takano Y, et al. Application of visante optical coherence tomography tear meniscus height measurement in theb diagnosis of dry eye disease. Ophthalmology, 2010,117(10): 1923-1929. DOI: 10.1016/j.ophtha.2010.01.057.
[12]
Akiyama R, Usui T, Yamagami S. Diagnosis of dry eye by tear meniscus measurements using anterior segment swept source optical coherence tomography. Cornea, 2015, 34 Suppl 11:S115-S120. DOI: 10.1097/ICO.0000000000000583.
archophthalmol.2009.356.
[5]
Schaumberg DA, Nichols JJ, Papas EB, et al. The international workshop on meibomian gland dysfunction: report of the subcommittee on the epidemiology of, and associated risk factors for, MGD. Invest Ophthalmol Vis Sci, 2011, 52(4): 1994-2005. DOI: 10.1167/iovs.10-6997e.
[6]
Han KE, Yoon SC, Ahn JM, et al. Evaluation of dry eye and meibomian gland dysfunction after cataract surgery. Am J Ophthalmol, 2014, 157(6): 1144-1150.e1. DOI: 10.1016/j.ajo.
[13]
Meibom H. De vasis palpebrarum novis epistola helmestadi:Typis ＆ sumptibus． Helmstadt: Henningi Muller, 1992: 34.
Savini G, Goto E, Carbonelli M, et al. Agreement between stratus and visante optical coherence tomography systems in tear meniscus measurements. Cornea, 2009, 28(2): 148-151. DOI:10.1097/ICO.0b013e31818526d0.
[11]
Ibrahim OM, Dogru M, Takano Y, et al. Application of visante optical coherence tomography tear meniscus height measurement in theb diagnosis of dry eye disease. Ophthalmology, 2010,117(10): 1923-1929. DOI: 10.1016/j.ophtha.2010.01.057.
[12]
Akiyama R, Usui T, Yamagami S. Diagnosis of dry eye by tear meniscus measurements using anterior segment swept source optical coherence tomography. Cornea, 2015, 34 Suppl 11:S115-S120. DOI: 10.1097/ICO.0000000000000583.
[15]
Nelson JD, Shimazaki J, Benitez-del-Castillo JM, et al. The international workshop on meibomian gland dysfunction:report of the definition and classification subcommittee. Invest
Ophthalmol Vis Sci, 2011, 52(4): 1930-1937. DOI: 10.1167/iovs.10-6997b.
浙公网安备 33030202001892号