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| Reconstruct the high myopic eye modules with 3D-MRI imaging technology |
| Shih Chingjung*,He Yuping,Zhao Tingting,Chen Qiuying,Hua Yihong,Hu Yunsheng,Li Nianyun,Zhang Lin,Zhang Guixiang,Fan Ying |
| Department of Ophthalmology, Shanghai First People′s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200080, China |
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Abstract Objective Analyze the shapes and features of high myopic eyes by 3D-MRI exanmination. To investigate 3D-MRI exanmination methods and imaging manifestations of high myopic eyes, and to evaluate its clinical values when comparing with other diagnostic imaging facilities. Methods 65 cases (124 eyes) of high myopic (the spherical diopter was equal or less than -6.00 diopter, and the eye axial length was equal or more than 26 mm) accepted the routine ophthalmologic examination and orbit MRI examination, among which, 40 cases (80 eyes) had ophthalmic B-type ultrasound exanmination. The MRI imaging were processed into 3D models. Patients were divided into groups by age (①<50 years, ②≥50 years), spherical diopter (①-6.00 D~-12.00 D, ②-12.25 D~ -18.00 D, ③-18.25 D~-24.00 D), and eye axial length (①26.00 mm~28.00 mm, ②28.01 mm~30.00 mm, ③30.01 mm~32.0 mm, ④>32.00 mm). The diagnostic accuracy of MRI examination and ophthalmic B-type ultrasound exanmination were analyzed by McNemar test, the correlation between eye shapes and case data were analyzed by chi square test. Results The diagnostic accuracy of the posterior staphyloma detected by ophthalmic B-type ultrasound exanmination was 70%, and was 100% by MRI examination, the positive rate of posterior staphyloma detected by MRI had significant difference (P<0.05) at the level of α=0.05 compared with those by ophthalmic B-type ultrasound. The shape of high myopia eyeball can be divided into four types: spherical, conical, bowl and column. The distribution of the four types of high myopic eye in the age grous and eye axial group had significant difference (P<0.05), and had no significant difference in the spherical diopter group. In some cases, irregular uplift and depression can be seen on the 3D-MRI model, but can not be accurately displayed in the ophthalmic B-type ultrasound exanmination. Conclusion 3D-MRI model can demonstrate high myopia eyeball shapes and the location and characteristics of posterior staphyloma. It has a higher diagnostic accuracy compared with ophthalmic B-type ultrasound and can be taken as a new method of high myopia eye examination.
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Received: 05 February 2016
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Corresponding Authors:
Fan Ying, Email: fanying0129@163.com
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