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| Comparison of corneal topography after topography-guided FS-LASIK and wavefront-optimized FS-LASIK |
| Zhang Li, Zhou Yuehua, Xu Wen, Li Ying, Wang Yue, Zhang Qiulu, Liu Jing, Hu Yabin |
| Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing 100730, China |
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Abstract Objective To compare the outcomes of topography-guided LASIK and wavefront-optimized LASIK in eyes of patients undergoing femtosecond laser LASIK (FS-LASIK) for myopia with astigmatism. Methods In this prospective clinical study, 44 eyes of 22 patients underwent topography-guided LASIK (topography group) and 43 eyes of 22 patients underwent wavefront-optimized LASIK (wavefront group). The topography treatment was based on data generated by a networked diagnostic device: Wavelight Topolyzer. Visual acuity, refractive error, the index of corneal surface variance (ISV), corneal wavefront aberrations and ablation decentration were evaluated 6 months postoperatively. Data were analyzed using independent t test. Results Six months postoperatively, there were no significant differences in UCVA or BCVA (t=-1.553, -1.570, P>0.05) between the groups. No eyes lost a line of BCVA in either group. There were no statistically significant differences in postoperative average sphere, cylinder refraction or spherical equivalent (SE) between the groups. The postoperative value of ISV increased compared to baseline for both groups (t=5.216, 7.870, P＜0.05). The mean postoperative ISV in the topography group (39.9±13.0) was significantly lower than that in the wavefront group (44.9±12.2) (t=-2.296, P<0.05). The postoperative mean decentration in the topography group (0.24±0.29 mm) was less than that in the wavefront group (0.29±0.31 mm), but the difference was not statistically significant (t=-1.005, P>0.05). There were significant differences in postoperative coma aberrations (Z31) [-0.166±0.357 μm vs. -0.362±0.353 μm, t=2.325, P<0.05] and spherical aberrations (Z40) [0.390±0.263 μm vs. 0.486±0.164 μm, t=-2.096, P<0.05] between the two groups． Conclusion Both topography-guided ablation and wavefront-optimized ablation provide good visual acuity and refractive results, but the former treatment results in a better index of corneal surface variance and induces fewer corneal aberrations.
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Corresponding Authors:
Zhou Yuehua, Email: yh0220@yahoo.com
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