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| Optical components of myopic children with a history of retinopathyof prematurity |
| XIE Li,WANG Ping,LUO Yi,MA Lan,LUO Jun,LI Na |
| Department of Ophthalmology, Hunan Children′s Hospital, the Pediatric College of the University of South China, Changsha 410007, China; Department of Ophthalmology, the Maternal and Child Healthcare Hospital of Xiangtan City, Xiangtan 411104, China; Changsha Honglang Eye Hospital, Changsha 410004, China |
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Abstract Objective To examine the changes in lens parameters in pre-school myopic children with a history of retinopathy of prematurity (ROP) and to identify the relationship between lens parameters and myopia with ROP. Methods In this cases control study, 66 children (126 eyes) aged 1 to 6 years were recruited from the Department of Ophthalmology in Hunan Children's Hospital from January 2014 to December 2015. ROP surgical patients were excluded. They were divided into the following two groups based on gestational age, history of ROP, and refractive status: (1)myopia with a history of ROP (36 cases, 68 eyes, MOR group) and (2) no myopia with ROP (30 cases, 58 eyes, Non-MOR group). Differences in optical parameters and lens thickness variation before and after cycloplegia were compared. Data between two groups were compared by t-test. Results For children aged 1-3 years, the MOR group had a steeper corneal curvature (t=2.916, P＜0.01) and greater lens thickness (LT) (t=3.227, P＜0.01) than did the non-MOR group. For children aged 4-6 years, only the LT of the MOR group was thicker (t=2.257, P＜0.05). The MOR group had a thicker LT before cycloplegia (t=3.152, P＜0.01) and less lens thickness variation before and after cycloplegia (t=2.045, P＜0.05) compared to the non-MOR group. Conclusion (1)In pre-school children, ROP myopia derives mainly from the increase in lens power. (2)Myopic children with ROP have a thicker lens. The change in the LT before and after mydriasis is small, suggesting that ROP may affect the elasticity and regulation of the lens. (3)The adjustment function of the lens and the matching optical components may be one of the important factors in the myopia of ROP.
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Received: 07 December 2016
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| Fund: Hunan Provincial Science and Technology Department of International Cooperation in Key Projects (2015WK3048) |
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Corresponding Authors:
WANG Ping, Email: wangping22@sina.com
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