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The Distribution of Astigmatism in Children and Adolescents in WenzhouArea and Risk Factor Analysis |
Haishuang Lin, Hua Zhou, Xiaoman Li, Longfei Jiang, Keke Li, Zhu Lin, Jie Chen, Fan Lu |
Ophthalmology and Optometry College and Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China |
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Abstract Objective: To evaluate the distribution of astigmatism in children and adolescents in the Wenzhou area and determine the correlation of astigmatism with related risk factors, such as parents’ astigmatism, age, gender, and body mass index (BMI). Methods: This was a cross-sectional study conducted in cooperation with the Eye Hospital and the Second Affiliated Hospital of Wenzhou Medical University. Subjects came from the Children’s Health Examination Center of the Second Affiliated Hospital of Wenzhou Medical University, from September 2011 to March 2016. Ophthalmology exams included entrance tests (visual acuity, pupil reaction, extraocular muscles, etc.) and cycloplegic refraction. Each child’s height, weight, bust, waist, and hips were also measured. For this study, astigmatism was considered when the cylinder was higher than or equal to 0.5 diopter (D) in the right eye. The non-cycloplegic refractive status of the parents were measured for further analysis. Rank sum test, chi-square test and logistic regression analysis were used toanalyze the distribution of astigmatism in children and adolescents and its risk factors. Results: A total of 525 subjects were examined, and 83.4% (438/525) completed the study. The prevalence of astigmatism was 59.4% (260). The percent of subjects with astigmatism between 0.50 D and 1.00 D was 80.8%, and the
percent between 1.25 D and 2.00 D was 11.2%. The percent with astigmatism higher than 2.00 D was 8.1%. Obese children tended to have a higher prevalence of astigmatism ( χ2=6.347, P=0.042) compared with nonobese children. With the rule (WTR) astigmatism was predominant (73.8%), and there was no significant difference in the astigmatism axis distribution between males and females (χ2=3.104, P=0.212) or among the different age groups (χ2=10.578, P=0.102). In the analysis of risk factors, the prevalence of astigmatism was higher in children with at least one astigmatic parent (χ2=7.484, P=0.024) compared with the children without an astigmatic parent. Logistic regression analysis indicated that the main factor that influenced the development of children and adolescents's astigmatism was the cylinder of mother (odds ratio=2.2, 95% confidence interval: 1.1-4.4, P=0.023). Conclusions: The prevalence of astigmatism in children and adolescents was 59.4% in Wenzhou area, and WTR was predominant. The astigmatism of the mother may
increase the risk of astigmatism in children and adolescents.
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Received: 22 February 2017
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Corresponding Authors:
Fan Lu, Ophthalmology and Optometry College and Eye Hospital, Wenzhou Medical
University, Wenzhou 325027, China (Email: lufan@mail.eye.ac.cn)
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[1] |
瞿佳. 视光学理论和方法. 人民卫生出版社, 2004:83.
|
[2] |
HuynhSC, KifleyA,RoseKA,etal.Astigmatismin 12-year-old Australian children: comparisons with a 6-year-old population. Invest Ophthalmol Vis Sci, 2007, 48(1): 73-82. DOI: 10.1167/iovs. 06-0263.
|
[3] |
HuynhSC,KifleyA,RoseKA,etal.Astigmatismanditscomponents in 6-year-old children. Invest Ophthalmol Vis Sci, 2006, 47(1): 55-64. DOI: 10.1167/iovs.05-0182.
|
[4] |
Tong L, Saw SM, Lin Y, et al. Incidence and progression of astigmatism in Singaporean children. Invest Ophthalmol Vis Sci, 2004, 45(11): 3914-3918. DOI: 10.1167/iovs.04-0492.
|
[5] |
Shih YF, Hsiao CK, Tung YL, et al. The prevalence of astigmatism in Taiwan schoolchildren. Optom Vis Sci, 2004,81(2):94-98.
|
[6] |
Orlansky G, Wilmer J, Taub MB, et al. Astigmatism and early academic readiness in preschool children. Optom Vis Sci, 2015, 92(3): 279-285. DOI: 10.1097/OPX.0000000000000485.
|
[7] |
Lai YH, Hsu HT, Wang HZ, et al. Astigmatism in preschool children in Taiwan. J AAPOS, 2010, 14(2): 150-154. DOI: 10.1016/j.jaapos.2009.12.168.
|
[8] |
Hashemi H, Hatef E, Fotouhi A, et al. Astigmatism and its determinants in the Tehran population: the Tehran eye study. Ophthalmic Epidemiol, 2005,12(6):373-381. DOI: 10.1080/ 09286580500281214.
|
[9] |
李春燕, 陈洁, 陈岩, 等. 杭州市6~15岁儿童散光现况. 中国学校卫生, 2012, 33(12): 1460 -1463.
|
[10] |
石庚生. 学龄前儿童散光与体格发育水平关系的探讨.现代医药卫生, 2012, 28(6): 826 -827.
|
[11] |
陈艳艳, 吴晓红, 李兴, 等. 散光对小学生屈光变化的影响观察.中国斜视与小儿眼科杂志, 2014, (1): 24 -24,51.
|
[12] |
Read SA, Collins MJ, Carney LG. A review of astigmatism and its possible genesis. Clin Exp Optom, 2007, 90(1): 5-19. DOI: 10.1111/j.1444-0938.2007.00112.x.
|
[13] |
Twelker JD, Miller JM, Sherrill DL, et al. Astigmatism and myopia in Tohono O'odham Native American children. Optom Vis Sci, 2013, 90(11): 1267-1273. DOI: 10.1097/OPX.0000000000000065.
|
[14] |
Fan DS, Rao SK, Cheung EY, et al. Astigmatism in Chinese preschool children: prevalence, change, and effect on refractive development. Br J Ophthalmol, 2004, 88(7): 938-941. DOI: 10.1136/bjo.2003.030338.
|
[15] |
Abrahamsson M, Sjöstrand J. Astigmatic axis and amblyopia in childhood. Acta Ophthalmol Scand, 2003, 81(1): 33-37.
|
[16] |
Brown SA, Weih LM, Fu CL, et al. Prevalence of amblyopia and associated refractive errors in an adult population in Victoria, Australia. Ophthalmic Epidemiol, 2000, 7(4): 249-258.
|
[17] |
Hammond CJ, Snieder H, Gilbert CE, et al. Genes and environment in refractive error: the twin eye study. Invest Ophthalmol Vis Sci, 2001, 42(6): 1232-1236.
|
[18] |
Dirani M, Islam A, Shekar SN, et al. Dominant genetic effects on corneal astigmatism: the genes in myopia (GEM) twin study. Invest Ophthalmol Vis Sci, 2008, 49(4): 1339-1344. DOI: 10.1167/ iovs.07-1011.
|
[19] |
中国肥胖问题工作组. 中国学龄儿童青少年超重、肥胖筛查体重指数值分类标准.中华流行病学杂志, 2004, 25(2): 97 -102. DOI: 10.3760/j.issn:0254-6450.2004.02.003.
|
[20] |
Fozailoff A, Tarczy-Hornoch K, Cotter S, et al. Prevalence of astigmatism in 6- to 72-month-old African American and Hispanic children: the Multi-ethnic Pediatric Eye Disease Study. Ophthalmology, 2011, 118(2): 284-293. DOI: 10.1016/j.ophtha. 2010.06.038.
|
[21] |
McKean-Cowdin R, Varma R, Cotter SA, et al. Risk factors for astigmatism in preschool children: the multi-ethnic pediatric eye disease and Baltimore pediatric eye disease studies. Ophthalmology, 2011, 118(10): 1974-1981. DOI: 10.1016/j.ophtha.2011.06.031.
|
[22] |
O'DonoghueL,BreslinKM,SaundersKJ.TheChangingProfile of Astigmatism in Childhood: The NICER Study. Invest Ophthalmol Vis Sci, 2015, 56(5): 2917-2925. DOI: 10.1167/iovs. 14-16151.
|
[23] |
任兵, 高晓唯, 罗英, 等. 5~12岁儿童散光度逐年变化的连续观察. 临床眼科杂志,2003, 11(4): 363 -364. DOI: 10.3969/j.issn. 1006-8422.2003.04.032.
|
[24] |
Fotouhi A, Hashemi H, Yekta AA, et al. Characteristics of astigmatism in a population of schoolchildren, Dezful, Iran. Optom Vis Sci, 2011, 88(9): 1054-1059. DOI: 10.1097/OPX. 0b013e318221727d.
|
[25] |
Grosvenor T. Etiology of astigmatism. Am J Optom Physiol Opt, 1978, 55(3): 214-218.
|
[26] |
Osaki T, Osaki MH, Osaki TH, et al. Influence of involuntary
|
|
eyelid spasms on corneal topographic and eyelid morphometric changes in patients with hemifacial spasm. Br J Ophthalmol, 2016, 100(7): 963-970. DOI: 10.1136/bjophthalmol-2015-307272.
|
[27] |
Kame RT, Jue TS, Shigekuni DM. A longitudinal study of corneal astigmatism changes in Asian eyes. J Am Optom Assoc, 1993, 64(3): 215-219.
|
|
|
|