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Fourier Analysis for Comparing the Accuracy of Myopic AstigmatismCorrection by FS-LASIK and TPRK |
Lu Jiang,Wen Xie,Zhongli Hu,Haitao Zhou,Peng Xu,Liang Hu,Fan Lu. |
School of Ophthalmology and Optometry,Wenzhou Medical University, Wenzhou 325027, China |
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Abstract Objective: To use Fourier analysis to evaluate the accuracy of myopic astigmatism correction in femtosecond laser in situ keratomileusis (FS-LASIK) and transepithelial photorefractive keratectomy(TPRK). Methods: A total of 267 myopic astigmatism patients (453 eyes) were included in this retrospective case group study. Patients were treated with either FS-LASIK (n=137, 228 eyes) or TPRK (n=130,225 eyes) at the Eye Hospital of Wenzhou Medical University from June, 2015 to June, 2016. Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), refraction, and corneal topography were measured preoperatively and postoperatively at 3 to 6 months. Fourier analysis was used to transform the preoperative astigmatism to TJ0 and TJ45, the preoperative corneal astigmatism to CJ0 and CJ45, the postoperative residual astigmatism to RJ0 and RJ45, and the astigmatism correction rate to CRJ0 and CRJ45.Covariance rank sum test, Mann-Whitney U test, and Wilcoxon signed rank sum test were used for statistical analyses. Results: For the FS-LASIK group, TJ0=0.369 D, TJ45=-0.043 D, CJ0=0.695 D, CJ45=-0.018 D,RJ0=0.000 D, RJ45=0.000 D, CRJ0=100%, CRJ45=100%. For the TPRK group, TJ0=0.369 D, TJ45=0.000 D,CJ0=0.600 D, CJ45=0.003 D,RJ0=0.000 D, RJ45=0.000 D, CRJ0=100%, CRJ45=100%. Comparing betweenFS-LASIK and TPRK, the values for TJ0, TJ45, CJ45, RJ45, CRJ45 were not statistically significant (P>0.05).CJ0 and RJ0 in the FS-LASIK group were higher than in the TPRK group (Z=-2.615, P=0.009; Z=-2.419,P=0.016). CRJ0 in the TPRK group was significantly higher than in the FS-LASIK group (Z=-1.978,P=0.048). For intra-group comparisons, TJ0 and CJ0 were statistically higher than TJ45 and CJ45 in the FSLASIK group (Z=-10.886, -12.926, both P<0.001). RJ0 and RJ45, and CRJ0 and CRJ45 were not significantly different. TJ0 and CJ0 were statistically higher than TJ45 and CJ45 in the TPRK group (Z=-10.539, -12.735, both P<0.001). RJ0 and RJ45, and CRJ0 and CRJ45 were not significantly different. Conclusions: Both FS-LASIK and TPRK have high accuracy in the correction of cartesian astigmatism and oblique astigmatism.
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Received: 12 May 2017
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Fund: This study was funded by Zhejiang Provincial Natural Science Foundation (LY17H120005), and Wenzhou Science and Technology Science Program (Y20160442) |
Corresponding Authors:
Fan Lu, School of Ophthalmology and Optometry,Wenzhou Medical University,Wenzhou 325027, China (Email: lufan@mail.eye.ac.cn)
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