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| Genetics of Fuchs Endothelial Corneal Dystrophy |
| Haiyue Yu,Meizhu Chen |
Department of Ophthalmology, Fuzhou General Hospital of Nanjing MilitaU Command, PLA, Dongfang;
Hospital Affiliated to Xiamen University, Clinical Medical College of Fujian Medical University, Clinical;
Medical College of the Second Military Medical University, Fuzhou 350025, China. |
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Abstract Fuchs endothelial comeal dystrophy (FECD) is one of the most common indicators for comeal transplantation caused by accidents. Previously, FECD was not common in our country, but now an mcreasing number of FECD patients are diagnosed in concurrence with the development of ophthalmology. As a result, the
pathogenesis of FECD has gradually gained more attention. The pathogenesis of FECD is highly complex;it is the result of the interaction between genetic and environmental factors. In this paper, we focus on the genetic basis of FECD. Studying the genetic basis can foster a better understanding of the pathogenesis of
FECD and lay a foundation for finding a non-surgical treatment for it.
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Received: 12 February 2017
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Corresponding Authors:
Meizhu Chen, Department of Ophthalmology, Fuzhou General Hospital of Nanjing
Military Command, PLA, Dongfang Hospital Affiliated to Xiamen University, Clinical Medical College of
Fujian Medical University, Clinical Medical College of the Second Military Medical University, Fuzhou
350025. China (Email: jumychen@tom.com)
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