Objective: To evaluate the safety, effectiveness, predictability, stability, and centrality of the automatic location tracking system contoura for the correction of ametropia with mild irregular astigmatism.Methods: In this prospective study, 23 consecutive patients (40 eyes) with ametropia and mild irregular astigmatism were studied from March to June 2016 at Hangzhou MSK Eye Hospital. Corrective surgery was performed using contoura, an automatic location tracking system. Uncorrected visual acuity, best corrected visual acuity, manifest refraction, and three-dimensional corneal topography were quantitatively assessed preoperatively and at 1 day, 2 weeks, and 3 months postoperatively. The results were analyzed with Pearson correlation analysis and one-way analysis of variance. Results: At 1 day, 2 weeks, and 3 months postoperatively, uncorrected visual acuity was -0.04±0.08, -0.06±0.08, -0.06±0.08 respectively.For all eyes, the best corrected visual acuity was equal to or higher than the preoperative values, and 32.5% of the eyes improved by 1 line while 2.5% improved by 2 lines at 3 months postoperatively. The actual corrected spherical equivalent was positively correlated with the predicted correction (r =0.999,P < 0.001). For residual spherical equivalent, all eyes were within ±0.50 D and 37.5% were within ±0.25 D.Uncorrected visual acuity and spherical equivalent were not statistically significant at each time point. The eccentric distances was statistically significant between 1 day and 3 months postoperatively (P=0.02).There were no significant differences among the remaining time points. All operations were successful, and no serious complications were seen during the 3-month postoperative period. Conclusions: The automatic positioning and tracking system contoura is safe, effective, predictive, stable, and centered for correction of ametropia with mild irregular astigmatism.