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| Characteristics of Angle Kappa in Cataract Patients and Changes under Photopic and Mesopic Conditions |
| Mengqiong Li, Zuhong Mao, Guangbin Zhang |
| The Affiliated Eye Center of Xiamen University, Xiamen 361000, China |
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Abstract Objective: To observe the characteristics and rule of change of the angle Kappa in cataract patients under photopic and mesopic conditions. Methods: In this case series study, a total of 788 eyes in 394 cataract patients receiving cataract surgery in the Affiliated Eye Center of Xiamen University were selected from May 2016 to October 2017. All patients were examined by OPD-Scan Ⅲ. The collected data included the clinical data of patients (such as age, gender, ocular history and surgical history), as well as preoperative biometric data, including mean corneal keratometry (mean K), and corneal spherical aberration (CSA), white-to-white distance (WTW), photopic pupil diameter (Photopic), mesopic pupil diameter (Mesopic), distance and angle of photopic angle Kappa (PDist@Angle), distance and angle of mesopic angle Kappa (MDist@Angle), and distance and angle from the mesopic pupil center to the photopic pupil center (MPDist@Angle) and so on. Specific tests included Rank sum test, Chi-square test, and multiple regression statistical analysis. Results: There were no significant differences in the biometric data, such as mean K, MPDist, PDist, WTW, and CSA between the two eyes (P>0.05), but the differences in photopic pupil diameter, mesopic pupil diameter, and MDist between the two eyes were statistically significant (Z=2.276, 3.284, 2.388, all P<0.05). The angle Kappa for most patients in the two eyes under photopic or mesopic conditions was positive, and the pupil center usually shifted inferotemporally when the illumination was changed from photopic to mesopic. The clinical and biometric data for both eyes were analyzed by multiple regression analysis with MPDist. The regression equation of the right eye was MPDist=0.033+0.505×MDist+0.041×CSA-0.319×PDist (F=45.0, P<0.001), while that of the left eye was MPDist=-0.002+0.547×MDist+0.013×Mesopic-0.350×PDist (F=61.6, P<0.001). Conclusions: In cataract patients, most eyes have a positive angle Kappa, and the variation in pupil size under different illuminations affect the size of the angle Kappa. Large differences can be detected in photopic pupil size, mesopic pupil size and the direction and shift of the pupil center during photopic and mesopic alternation. There was a linear regression relationship between MPDist changes and PDist, MDist, Mesopic, CSA. Among them, MPDist of both eyes were negatively correlated with PDist, and MDist of both eyes had relatively larger influence on MPDist changes.
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Received: 18 January 2019
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| Fund:Science and Technology Benefiting Project of Xiamen City (3502Z20174001) |
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Corresponding Authors:
Corresponding author: Guangbin Zhang, the Affiliated Eye Center of Xiamen University, Xiamen 361000, China (Email: 386975604@qq.com)
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| [1] |
Park CY, Oh SY, Chuck RS.Measurement of angle kappa and centration in refractive surgery. Curr Opin Ophthalmol, 2012, 23(4): 269-275. DOI: 10.1097/ICU.0b013e3283543c41.
|
| [2] |
Prakash G, Prakash DR, Agarwal A, et al.Predictive factor and kappa angle analysis for visual satisfactions in patients with multifocal IOL implantation. Eye (Lond), 2011, 25(9): 1187-1193. DOI: 10.1038/eye.2011.150.
|
| [3] |
Tchah H, Nam K, Yoo A.Predictive factors for photic phenomena after refractive, rotationally asymmetric, multifocal intraocular lens implantation. Int J Ophthalmol, 2017, 10(2): 241-245. DOI: 10.18240/ijo.2017.02.10.
|
| [4] |
Gholami S, Reus NJ, van den Berg T. The significance of changes in pupil size during straylight measurement and with varying environmental illuminance. J Optom, 2018, 11(3): 167-173. DOI: 10.1016/j.optom.2017.08.004.
|
| [5] |
Alio JL, Plaza-Puche AB, Férnandez-Buenaga R, et al.Multifocal intraocular lenses: An overview. Surv Ophthalmol, 2017, 62(5): 611-634. DOI: 10.1016/j.survophthal. 2017.03.005.
|
| [6] |
Moshirfar M, Hoggan RN, Muthappan V.Angle Kappa and its importance in refractive surgery. Oman J Ophthalmo, 2013, 6(3): 151-158. DOI: 10.4103/0974-620X.122268.
|
| [7] |
Visser N, Bauer NJ, Nuijts RM.Toric intraocular lenses: Historical overview, patient selection, IOL calculation, surgical techniques, clinical outcomes, and complications. J Cataract Refract Surg, 2013, 39(4):624-637. DOI: 10.1016/j.jcrs.2013.02. 020.
|
| [8] |
Fujikado T, Saika M.Evaluation of actual retinal images produced by misaligned aspheric intraocular lenses in a model eye. Clin Ophthalmol, 2014, 8: 2415-2423. DOI: 10.2147/OPTH.S72053.
|
| [9] |
陈琛, 叶剑, 黄婵娟, 等. 不同Kappa角眼多焦点人工晶状体植入术后的视觉质量. 中华眼视光学与视觉科学杂志, 2016, 18(5): 298-301. DOI: 10.3760/cma.j.issn.1674-845X.2016.05. 010.
|
| [10] |
赵堪兴, 杨培增. 眼科学. 8版. 北京: 人民卫生出版社,2017: 8, 23-24, 50-51.
|
| [11] |
Winn B, Whitaker D, Elliott DB, et al.Factors affecting light adapted pupil size in normal human subjects. Invest Ophthalmol Vis Sci, 1994, 35(3): 1132-1137.
|
| [12] |
Kohnen E-M, Zubcov AA, Kohnen T.Scotopic pupil size in a normal pediatric population using infrared pupillometry. Graefes Arch Clin Exp Ophthalmol, 2004, 242(1): 18-23. DOI: 10.1007/s00417-003-0735-4.
|
| [13] |
Kasthurirangan S, Glasser A.Age related changes in the characteristics of the near pupil response. Vision Res, 2006, 46(8-9): 1393-1403. DOI: 10.1016/j.visres.2005.07.004.
|
| [14] |
Donnenfeld E.The pupil is a moving target: Centration, repeatability, and registration. J Refract Surg, 2004, 20(5): S593-596.
|
| [15] |
Yang Y, Thompson K, Burns SA.Pupil location under mesopic, photopic, and pharmacologically dilated conditions. Invest Ophthalmol Vis Sci, 2002, 43(7): 2508-2512.
|
| [16] |
Erdem U, Muftuoglu O, Gundogan FC, et al.Pupil center shift relative to the coaxially sighted corneal light reflex under natural and pharmacologically dilated conditions. J Refract Surg, 2008, 24(5): 530-538. DOI: 10.3928/1081597X-20080501-12.
|
| [17] |
Hashemi H, KhabazKhoob M, Yazdani K, et al. Distribution of angle kappa measurements with Orbscan Ⅱ in a population-based survey. J Refract Surg, 2010, 26(12): 966-971. DOI: 10.3928/1081597X-20100114-06.
|
| [18] |
Basmak H, Sahin A, Yildirim N, et al.Measurement of angle kappa with synoptophore and Orbscan Ⅱ in a normal population. J Refract Surg, 2007, 23(5): 456-460.
|
| [19] |
Basmak H, Sahin A, Yildirim N, et al.The angle kappa in strabismic individuals. Strabismus, 2007, 15(4): 193-196. DOI: 10.1080/09273970701631926.
|
|
|
|
2019, Vol. 21 
