新型冠状病毒核酸检测在眼科医院疫情防控中的实践与有效性研究

doi:10.3760/cma.j.cn115909-20200303-00063

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Abstract Objective: To explore a practical system for precision prevention and control against coronavirus disease 2019 (COVID-19) for eye hospitals by emphasizing systematic and standardized virus RNA detection procedures. Methods: In this case series study, standardized virus RNA detection along with a routine blood test (BRT), C-reactive protein (CRP) and serum amyloid A (SAA) were included in preoperative screening test items for ocular surgical patients and to provide virus RNA detection for returning employees between 24 February 2020 and 2 March 2020. In addition, a questionnaire was designed to investigate the acceptability of nasopharyngeal swab sampling and the influence of virus RNA detection results on the mental status of the examinee. Results: Ninety-nine examination results showed a certain percentage of abnormal test results, among which 13 cases showed an increase in SAA, 12 cases showed a decrease in lymphocyte count (LYM) while 5 cases showed an increase, 1 case showed a decrease in white blood count (WBC) while 11 cases showed an increase, and 2 cases showed an increase in CRP. All cases tested negative for novel coronavirus (2019-nCoV) RNA detection, including examined patients and 33 employees of the Eye Hospital. 11.7% of respondents reported a low acceptance score for nasopharyngeal swab sampling. The proportion of the examinees with higher mental stress scores before and after the virus RNA detection test was 46.7% and 6.7%, respectively. Conclusions: The detection procedures can offer an objective basis for preoperative screening and differential diagnosis, while largely eliminating the possibility of transmission via asymptomatic infected individuals. On the other hand, the negative result of virus RNA detection is beneficial in adjusting a patient's preoperative psychological state and relieving the mental stress of medical staff during the epidemic.

Key words： coronavirus disease 2019 novel coronavirus infection epidemic prevention and control RNA detection ophthalmology effectiveness

Received: 03 March 2020

Fund:Wenzhou Municipal City Emergency Research Grant for Prevention of 2019nCon Virus (ZY2020001)

Corresponding Authors: Jia Qu, Eye Hospital, Wenzhou Medical University, National Clinical Research Center for Ocular Disease, Wenzhou 325027, China (Email: 13806898805@163.com)

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https://www.cjoovs.com/EN/10.3760/cma.j.cn115909-20200303-00063 OR https://www.cjoovs.com/EN/Y2020/V22/I4/247

[1]	国卫办医涵〔2020〕145号. 新型冠状病毒感染的肺炎诊疗方案（试行第六版）. （2020-02-19）[2020-02-26] http://www. nhc.gov.cn/yzygj/s7653p/202002/8334a8326dd94d329df351d7d a8aefc2.shtml.
[2]	Wei-jie Guan, Z Ni, YU HU, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med, DOI: 10.1056/NEJMoa2002032.
[3]	Yanfang Jiang, Haifeng Wang, Yukun Chen, etc. Clinical Data on Hospital Environmental Hygiene Monitoring and Medical Staffs Protection during the Coronavirus Disease 2019 Outbreak. [J/OL]. medRxiv https://www.medrxiv.org/content/10.1101/202 0.02.25.20028043v1.full.pdf.
[4]	董家鸿, 冯晓彬, 杨世忠, 等. 打赢疫情“阻击战”后方不可 “不设防”. 中华消化外科杂志, 2020, 19(3): 225-228. DOI: 10.3760/cma.j.issn.1673-9752.2020.03.001.
[5]	郑美琴, 吴文灿, 陈蔚, 等. 新型冠状病毒肺炎防控期间眼专科机构开展病毒核酸检测的必要性和可行性评估 [J/OL]. 中华实验眼科杂志, 2020, 38(3): 257-260. DOI:10.3760/cma. j.cn115989-20200224-00105.
[6]	严杰, 李明远, 孙爱华, 等. 2019-新型冠状病毒及其感染性肺炎. 中华微生物学和免疫学杂志, 2020, 40(1): 1-6. DOI: 10.3760/cma.j.issn.0254-5101.2020.01.001.
[7]	周翔天, 瞿佳. 新型冠状病毒与眼，我们所知道的与我们应该做的. 中华眼视光学与视觉科学杂志, 2020, 22(00): E001-E001. DOI: 10.3760/cma.j.issn.1674-845X.2020.0001.
[8]	李雪杰, 汪明, 陈长征, 等. 伴发或首发病毒性结膜炎的新型冠状病毒感染下眼科医师的防控策略[J/OL]. 中华实验眼科杂志, 2020, 38(3): 276-280. DOI: 10.3760/cma.j.issn.2095- 0160.2020.0002.
[9]	叶娅, 宋艳萍, 闫明, 等. 新型冠状病毒肺炎合并结膜炎三例. 中华实验眼科杂志, 2020, 38(3): 242-244. DOI: 10.3760/cma. j.issn.2095-0160.2020.0006.
[10]	晋秀明, 林琳, 黄晓丹. 2019新型冠状病毒经眼表传染的可能机制和防控措施. 中华眼科杂志, 2020, 56 [2020-02-23]. http://rs.yiigle.com/yufabiao. DOI: 10.3760/cma.j.cn112142- 20200214-00063.
[11]	国卫办医涵〔2020〕80号新型冠状病毒感染的肺炎实验室检测技术指南（第三版）. 2020-01-28.
[12]	中华预防医学会公共卫生眼科分会, 北京医学会眼科专业委员会及眼科专业青年委员会. 新型冠状病毒疫情期间眼科防护专家建议. 中华眼科杂志, 2020, 56(00): E002-E002. DOI: 10.3760/cma.j.issn.0412-4081.2020.0002.
[13]	国发明电〔2020〕4号. 国务院应对新型冠状病毒感染肺炎疫情联防联控机制关于印发企事业单位复工复产疫情防控措施指南的通知. 2020-02-22[2020-02-26]. http://www.nhc.gov. cn/zyjks/gongw/202002/e6dad55e209a4a46b9f003cd06080997. shtml.
[14]	人民网. 夏婕妤, 趙用. 温州: 复工企业可申请新冠肺炎核酸检测服务. 2020-02-21[2020-02-26]. http://zj.people.com.cn/ BIG5/n2/2020/0221/c186951-33815286.html.
[15]	中华医学会检验医学分会. 新型冠状病毒肺炎病毒核酸检测专家共识. 中华医学杂志, 2020, 100(00): E003-E003. DOI: 10.3760/cma.j.issn.0376-2491.2020.0003.
[16]	国卫办医涵〔2020〕184号新型冠状病毒感染的肺炎诊疗方案（试行第七版）. 2020-03-03[2020-03-04].
[17]	莫茜, 秦炜, 傅启华, 等. 正确认识新冠病毒核酸检测的影响因素. 中华检验医学杂志, 2020, 43(00): E002-E002. DOI: 10.3760/cma.j.issn.1009-8158.2020.0002.
[18]	徐万洲, 李娟, 何晓云, 等. IgM和IgG抗体联合检测在新冠病毒感染中的诊断价值. 中华检验医学杂志, 2020, 43(3): 230- 233. DOI: 10.3760/cma.j.issn.1009-9158.2020.03.007.

[1]

Chinese Optometric Association, Chinese Ophthalmological Society; Ophthalmology and Optometry Committee, Ophthalmologists Association, Chinese Doctor Association; et al. Expert Consensus on Multifocal Soft Contact Lens Fitting for Myopia Control (2023)[J]. Chinese Journal of Optometry Ophthalmology and Visual science, 2023, 25(8): 561-567.