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The Importance to the Association between Myopia and Glaucoma |
Yehong Zhuo, Jian Ge |
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University,Guangzhou 510060, China |
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Guide |
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Abstract The present article reviews the crosslink between myopia and glaucoma, raising important issues yet to be demonstrated, and offering potential research directions. The areas in the present article include the correlation between different types of myopia and glaucoma and the research status of genetic, structural and functional fields. Ultimately, a better understanding of myopia and glaucoma and breakthroughs in the integrated interdisciplinary field may lead to improved intervention strategies in the future.
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Received: 08 June 2020
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Fund:National Natural Science Foundation of China (81870658) |
Corresponding Authors:
Yehong Zhuo, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China (Email: zhuoyh@mail.sysu.edu.cn)
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[1] |
Holden BA, Fricke TR, Wilson DA, et al. Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050. Ophthalmology, 2016, 123(5): 1036-1042. DOI: 10.1016/ j.ophtha.2016.01.006.
|
[2] |
He M, Xiang F, Zeng Y, et al. Effect of time spent outdoors at school on the development of myopia among children in China: A randomized clinical trial. JAMA, 2015, 314(11): 1142-1148. DOI: 10.1001/jama.2015.10803.
|
[3] |
Guo L, Yang J, Mai J, et al. Prevalence and associated factors of myopia among primary and middle school-aged students: a school-based study in Guangzhou. Eye (Lond), 2016, 30(6): 796-804. DOI: 10.1038/eye.2016.39.
|
[4] |
Boland MV, Quigley HA. Risk factors and open-angle glaucoma: classification and application. J Glaucoma, 2007, 16(4): 406-418. DOI: 10.1097/IJG.0b013e31806540a1.
|
[5] |
Shen L, Melles RB, Metlapally R, et al. The association of refractive error with glaucoma in a multiethnic population. Ophthalmology, 2016, 123(1): 92-101. DOI: 10.1016/j.ophtha. 2015.07.002.
|
[6] |
Marcus MW, de Vries MM, Junoy Montolio FG, et al. Myopia as a risk factor for open-angle glaucoma: A systematic review and meta-analysis. Ophthalmology, 2011, 118(10): 1989-1994. e2. DOI: 10.1016/j.ophtha.2011.03.012.
|
[7] |
Yang YX, Wang NL, Wu L, et al. Effect of high myopia on 24-hour intraocular pressure in patients with primary open-angle glaucoma. Chin Med J (Engl), 2012, 125(7): 1282-1286.
|
[8] |
Lauwen S, de Jong EK, Lefeber DJ, et al. Omics biomarkers in ophthalmology. Invest Ophthalmol Vis Sci, 2017, 58(6): BIO88- BIO98. DOI: 10.1167/iovs.17-21809.
|
[9] |
Cai XB, Shen SR, Chen DF, et al. An overview of myopia genetics. Exp Eye Res, 2019, 188: 107778. DOI: 10.1016/j.exer. 2019.107778.
|
[10] |
Youngblood H, Hauser MA, Liu Y. Update on the genetics of primary open-angle glaucoma. Exp Eye Res, 2019, 188: 107795. DOI: 10.1016/j.exer.2019.107795.
|
[11] |
Hsu CH, Chen RI, Lin SC. Myopia and glaucoma: Sorting out the difference. Curr Opin Ophthalmol, 2015, 26(2): 90-95. DOI: 10.1097/ICU.0000000000000124.
|
[12] |
Han X, Qassim A, An J, et al. Genome-wide association analysis of 95 549 individuals identifies novel loci and genes influencing optic disc morphology. Hum Mol Genet, 2019, 28(21): 3680- 3690. DOI: 10.1093/hmg/ddz193.
|
[13] |
Veth KN, Willer JR, Collery RF, et al. Mutations in zebrafish lrp 2 result in adult-onset ocular pathogenesis that models myopia and other risk factors for glaucoma. PLoS Genet, 2011, 7(2): e1001310. DOI: 10.1371/journal.pgen.1001310.
|
[14] |
Iglesias AI, Springelkamp H, Ramdas WD, et al. Genes, pathways, and animal models in primary open-angle glaucoma. Eye (Lond), 2015, 29(10): 1285-1298. DOI: 10.1038/eye.2015.160.
|
[15] |
Sawada Y, Araie M, Shibata H, et al. Optic Disc Margin Anatomic Features in Myopic Eyes with Glaucoma with Spectral-Domain OCT. Ophthalmology, 2018, 125(12): 1886- 1897. DOI: 10.1016/j.ophtha.2018.07.004.
|
[16] |
Jonas JB, Weber P, Nagaoka N, et al. Glaucoma in high myopia and parapapillary delta zone. PLoS One, 2017, 12(4): e0175120. DOI: 10.1371/journal.pone.0175120.
|
[17] |
Lee SH, Lee EJ, Kim TW. Comparison of vascular-function and structure-function correlations in glaucomatous eyes with high myopia. Br J Ophthalmol, 2020, 104(6): 807-812. DOI: 10.1136/ bjophthalmol-2019-314430.
|
[18] |
Na HM, Lee EJ, Lee SH, et al. Evaluation of peripapillary choroidal microvasculature to detect glaucomatous damage in eyes with high myopia. J Glaucoma, 2020, 29(1): 39-45. DOI: 10.1097/IJG.0000000000001408.
|
[19] |
Shin JW, Kwon J, Lee J, et al. Choroidal Microvasculature dropout is not associated with myopia, but is associated with glaucoma. J Glaucoma, 2018, 27(2): 189-196. DOI: 10.1097/ IJG.0000000000000859.
|
[20] |
Liu H, Li L, Wormstone IM, et al. Development and validation of a deep learning system to detect glaucomatous optic neuropathy using fundus photographs. JAMA Ophthalmol, 2019, 137(12): 1353-1360. DOI: 10.1001/jamaophthalmol.2019.3501.
|
[21] |
Ting DSW, Pasquale LR, Peng L, et al. Artificial intelligence and deep learning in ophthalmology. Br J Ophthalmol, 2019, 103(2): 167-175. DOI: 10.1136/bjophthalmol-2018-313173.
|
[22] |
Schmidt-Erfurth U, Sadeghipour A, Gerendas BS, et al. Artificial intelligence in retina. Prog Retin Eye Res, 2018, 67: 1-29. DOI: 10.1016/j.preteyeres.2018.07.004.
|
[23] |
He J, Baxter SL, Xu J, et al. The practical implementation of artificial intelligence technologies in medicine. Nat Med, 2019, 25(1): 30-36. DOI: 10.1038/s41591-018-0307-0.
|
|
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