i.Profiler和iTrace波前像差仪测量健康人眼波前像差的一致性

doi:10.3760/cma.j.cn115909-20200525-00217

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Abstract Objective: To evaluate the agreement between the i.Profiler and iTrace aberrometers for measuring wavefront aberrations in healthy young eyes and the correlation between corneal aberration and pupil diameter. Methods: Ninety-six healthy young eyes of 96 healthy young persons were examined by the i.Profiler and iTrace in this diagnostic test study. Corneal (2-6 mm pupil diameter) and ocular (3 mm and 5 mm pupil diameters) higher-order aberrations, including total higher-order aberrations (tHOA), fourth order (Z40 ) spherical aberration (SA), vertical coma (Z3 -1), horizontal coma (Z31 ), vertical trefoil (Z3 -3),and horizontal trefoil (Z33 ), were measured. Agreement between the two aberrometers was evaluated by a t-test, Pearson correlation, Bland-Altman and 95% limits of agreement (95%LoA). Results: The 95%LoA of the higher-order aberrations measured by i.Profiler and iTrace were relatively narrow, showing good agreement. At a 4 mm pupil diameter, corneal Z40 measured by i.Profiler and iTrace were 0.049±0.016 μm and 0.048±0.016 μm, respectively. At a 6 mm pupil diameter, corneal Z40 were 0.270±0.040 μm and 0.266±0.037 μm, respectively. At a 2-6 mm pupil diameter, corneal tHOA, SA (Z40 ), (Z3 -1), (Z31 ), (Z3-3) and (Z33 ) increased with an increase in pupil diameter. The corresponding correlation coefficients between corneal higher-order aberrations and pupil diameter were 0.960, 0.916, 0.978, 0.970, 0.982 and 0.984 when using i.Profiler (all P<0.05), and the counterparts were 0.960, 0.916, 0.983, 0.970, 0.984 and 0.969 when using iTrace (all P<0.05). At 3 mm and 5 mm pupil diameters, the measured ocular Z40 were 0.010±0.008 μm and 0.073±0.052 μm, respectively, which were smaller than corneal Z40 (0.016±0.007 μm and 0.116±0.031 μm) when using i.Profiler. Conclusions: The i.Profiler and iTrace show good agreement in measuring wavefront aberrations in healthy young eyes.

Key words： i.Profiler iTrace agreement corneal aberration ocular aberration pupil diameter

Received: 25 May 2020

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Fund: Key Project of Sichuan Health and Family Planning Commission (18ZD022); Key Project of Nanchong City and University Cooperation (18SXHZ0492)

Corresponding Authors: Changjun Lan, Department of Ophthalmology, Affiliated Hospital of North Sichuan Medical College, Department of Ophthalmology & Optometry, North Sichuan Medical College, Nanchong 637000, China (Email: lanchangjun@sina.com)

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https://www.cjoovs.com/EN/10.3760/cma.j.cn115909-20200525-00217 OR https://www.cjoovs.com/EN/Y2021/V23/I1/19

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