视觉功能分析仪和扫频光学生物测量仪测量白内障患者Kappa角与Alpha角的比较

doi:10.3760/cma.j.cn115909-20200903-00355

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Abstract Objective: To evaluate the difference, correlation, agreement and repeatability of angle kappa and angle alpha measured by a visual function analyzer and swept-source optical coherence tomography biometer. Methods: A series of case study was designed. One hundred sixty-four patients undergoing cataract surgery in our hospital from October 2018 to October 2019 were included. Data from their right eyes were selected for analysis in all patients. Angle kappa, angle alpha, and the corresponding pupil diameter and corneal diameter were measured by the iTrace visual function analyzer and IOLMaster 700 sweptsource optical coherence tomography biometer. Three repeated measurements were taken for each patient. A paired t test and Wilcoxon symbolic rank test were used to analyze the differences in measurement results. The Pearson correlation coefficient and Spearmen correlation coefficient were used to analyze the correlation. The 95% limits of agreement (LoA) of angle kappa and angle alpha measured by the two devices were calculated by the Bland-Altman method. The repeatability of angle kappa and angle alpha for the two devices was evaluated by the intraclass correlation coefficient (ICC). Results: The angle kappa, angle alpha, pupil diameter and corneal diameter were 0.26 mm (0.18, 0.38), 0.35±0.14 mm, 4.70 mm (4.22, 5.42) and 10.85±0.36 mm (iTrace), and were 0.23 mm (0.15, 0.34), 0.42±0.19 mm, 4.43 mm (3.74, 4.87) and 11.73±0.43 mm (IOLMaster 700), respectively. The angle kappas of the two devices showed no significant difference, while the angle alpha, pupil diameter and corneal diameter showed significant differences (t=-5.541, Z=-9.117, t=-49.463, all P<0.001). The angle kappa was above 0.5 mm in 5.4% of eyes in both devices. The angle alpha was above 0.5 mm in 14.0% (iTrace) versus 32.9% (IOLMaster 700) of eyes. The angle kappa and angle alpha measured by the two devices were moderately correlated (ρ=0.607, r=0.553, P<0.001). The 95%LoA of angle kappa and angle alpha of the two devices was 0.0164(-0.3032-0.3361 mm) and -0.0718(-0.3970-0.2534 mm), respectively. The ICC (95%CI) of angle kappa and angle alpha for iTrace was 0.771(0.689-0.832) and 0.771(0.688-0.832), respectively, and that of IOLMaster 700 was 0.823(0.759-0.870) and 0.863(0.814-0.899), respectively. Conclusions: Angle kappa measured by the two devices shows no difference. However, it is not directly interchangeable considering the difference in pupil diameter between the two devices. There is a significant difference in terms of angle alpha between the two devices, which is larger in IOLMaster 700. The angle alpha of iTrace is not directly interchangeable with that of IOLMaster 700.

Key words： angle kappa angle alpha swept-source optical coherence tomography biometer visual function analyzer cataract

Received: 03 September 2020

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Fund: Hunan Provincial Clinical Medical Technology Innovation Guiding Plan (2018SK50109); Medical Research Project of Wuhan Health Commission (WX17B22); Research Fund of Aier Eye Hospital Group (AM1902D1)

Corresponding Authors: Yong Wang, Aier School of Ophthalmology, Central South University, Changsha 410000, China; Aier Eye Hospital of Wuhan University, Wuhan 430061, China (Email: wangyongeye@163.com)

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https://www.cjoovs.com/EN/10.3760/cma.j.cn115909-20200903-00355 OR https://www.cjoovs.com/EN/Y2021/V23/I2/98

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