双通道视觉质量分析系统评价泪膜稳定性对青少年视网膜成像质量的影响

doi:10.3760/cma.j.cn115909-20201021-00406

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Abstract Objective: To evaluate the impact of tear film stability on adolescent visual quality by using the Optical Quality Analysis System (OQAS-II), and to provide relevant data for clinical research. Methods: In this case series study, 32 adolescent patients with short break-up time (BUT<10 s) and thirty control subjects (BUT≥10 s) were enrolled from the outpatient clinic of Fuzhou Hospital of Traditional Chinese Medicine from March to October 2019. The OQAS-II system was used to detect the modulation transfer function cut off frequency (MTF cutoff), objective scattering index (OSI) and OQAS values with contrasts of 100%, 20% and 9% (OV100%, OV20% and OV9%) in the natural state. Meanwhile, the dynamic changes of OSI were detected during 20-second intervals with the eye open continuously, and the mean value and standard deviation of OSI (SD-OSI) in this dynamic process were obtained. Differences in the parameters were compared between the two groups using independent t test. Spearman rank correlation analysis was used to analyze the correlation between the data. Results: There were no statistically significant differences between the two groups in terms of age, spherical degree or astigmatic degree. BUT was 5.90±2.16 s in the study group, which was significantly less than that in the control group (11.53±2.06 s). This difference (t=-10.473, P<0.001) was statistically significant. MTF cutoff, OSI, OV100%, OV20%, OV9% were compared between the 2 groups, and the differences were not statistically significant. The mean values of OSI and SD-OSI in the study group were higher than those in the control group, and the difference was statistically significant (t=2.259, P=0.028; t=0.359, P=0.036). There was no correlation between MTF cutoff, OSI, OV100%, OV20% and BUT (all P>0.05) but the value of OV9% was positively correlated with BUT (r=0.273, P=0.032). The mean value of OSI in 20-second period was negatively correlated with BUT (r=-0.276, P=0.002), while SD-OSI was not correlated with BUT. Conclusions: The instability of adolescent tear films can lead to a decline in retinal image quality, and it is related to the degree of BUT. There is a high value of OQAS-II in evaluation of adolescent tear films.

Key words： tear film visual quality Optical Quality Analysis System retinal imaging adolescent

Received: 21 October 2020

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Fund: Fuzhou Science and Technology Project (2018-S-102-6)

Corresponding Authors: Man Song, Department of Ophthalmology, Fuzhou Hospital of Traditional Chinese Medicine, Fuzhou 350001, China (Email: 4674977@qq.com)

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https://www.cjoovs.com/EN/10.3760/cma.j.cn115909-20201021-00406 OR https://www.cjoovs.com/EN/Y2021/V23/I2/116

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