温州医科大学附属眼视光医院温州院区激光角膜屈光手术方式十年变化趋势

doi:10.3760/cma.j.cn115909-20201209-00473

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Abstract Objective: To investigate the changing trends in the types of corneal laser refractive surgury in the Eye Hospital (Wenzhou Branch), Wenzhou Medical University, from 2010 to 2019. Methods: This was a retrospective case series study. Data for 35 902 patients (70 766 eyes), 22 372 men (43 973 eyes), 13 530 women (26 793 eyes); age range (median), 16-62 (22) years, who underwent corneal laser refractive surgery from January 1, 2010 to December 31, 2019 in the Eye Hospital (Wenzhou Branch), Wenzhou Medical University, were collected. Data for age and gender distribution of corneal laser refractive surgical cases and the changing trends in surgical quantity and type, and the seasonal trends were analyzed by SPSS 21.0 and R4.0.3. Results: The number of corneal laser refractive surgical cases increased compared with the previous years except for 2012 and 2014. The proportion of photorefractive keratectomy fluctuated between 0.10% and 0.19% from 2010 to 2012. The ratio of epipolis-laser in situ keratomileusis increased from 7.68% in 2010 to 8.71% in 2011, and then decreased to 0.03% (χ2 =1367.475, P<0.001) in 2016. The proportion of transepithelial photorefractive keratectomy increased from 3.20% in 2012 to 36.87% in 2019 (χ2 =4388.776, P<0.001). The rate of laser in situ keratomileusis was accounted for 92.21% in 2010, and then decreased to 0.22% in 2018 (χ2 =23052.398, P<0.001). The ratio of femtosecond laser-assisted laser in situ keratomileusis increased from 29.35% in 2011 to 72.90% in 2016 (χ2 =3635.744, P<0.001), but decreased to 31.41% in 2019 (χ2 =1107.074, P<0.001). The ratio of femtosecond laser small incision lenticule extraction increased between 2016 and 2019 from 4.11% to 31.72% (χ2 =2021.33, P<0.001). The big seasonal peak was from June to August every year, and the small peak was February. Conclusions: The quantity of corneal laser refractive surgery in the Eye Hospital (Wenzhou Branch), Wenzhou Medical University, showed a gradually increasing trend compared with the previous year except for the decrease in the early stage. Lamellar laser surgery was still the main stream surgical procedure, and the trend of surface laser surgery to regress was becoming more and more prominent. There were three main kinds of corneal laser refractive surgery in recent years: Transepithelial photo refractive keratectomy, femtosecond laser-assisted laser in situ keratomileusis and femtosecond laser small incision lenticule extraction. June to August and February were the months in which operations were concentrated every year.

Key words： corneal laser refractive surgery excimer laser femtosecond laser long-term change trend

Received: 09 December 2020

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Fund: Zhejiang Medical Science and Technology Program (2017KY113, 2018KY543)

Corresponding Authors: Qinmei Wang, Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou 325027, China; National Clinical Research Center for Ocular Diseases, Wenzhou 325027, China (Email: wqm3@mail.eye.ac.cn)

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