沈阳市眼健康筛查人群眼压分布

doi:10.3760/cma.j.cn115909-20201118-00445

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Abstract Objective: To investigate the distribution and influencing factors of intraocular pressure (IOP) in healthy people suspected to have ocular hypertension or glaucoma in a screened population in Shenyang. Methods: Cross sectional investigation study. From March 1st to September 30th, 2016, local urban residents aged 30 and over who had made an appointment for a physical examination at the Fourth People's Hospital of Shenyang were invited for this screening. Stratified random sampling was conducted according to the registered domicile of those screened. Enrolled participants underwent a bilateral examination of habitual visual acuity, noncontact pneumotonometry, and non-mydriatic fundus photography. Ocular hypertension was defined as IOP >21 mmHg (1 mmHg=0.133 kPa) in either eye with a normal fundus in both eyes. Suspected glaucoma was diagnosed if two or more glaucomatous optic nerve changes were detected. Distribution of intraocular pressure was analyzed in the different gender and age groups in the sample. Results: A total of 15 303 subjects were enrolled and final data from 12 374 participants were used for analysis according to the exclusion criteria, including 11 296 healthy persons (91.3%), 801 persons suspected to have ocular hypertension (6.5%), and 277 persons suspected to have glaucoma (2.2%). Mean age of the healthy individuals was 50±13 years, and the IOP was 16.2±2.2 mmHg. IOP in the left eye (16.3±2.3 mmHg) was higher than that in the right eye (16.0±2.3 mmHg) (t=-19.813, P<0.001). Women (16.1±2.3 mmHg) had a higher IOP than men (15.9±2.3 mmHg) (t=-3.264, P=0.001), and older individuals had lower IOP than the youngers (F=29.729, P<0.001). IOP for people suspected to have ocular hypertension (mean age, 49±13 years) was 21.7±2.3 mmHg. IOP (18.0±4.0 mmHg) in people suspected to have glaucoma (mean age, 56±13 years) was significantly higher than that in healthy people, but lower than those suspected to have ocular hypertension (F=2300, P<0.001). Only 16.6% of these glaucoma suspects showed an IOP of 21 mmHg or higher. Age and gender did not exert influence on the IOP in people suspected to have ocular hypertension or glaucoma. Conclusions: IOP decreases with age in the adult population in Shenyang. IOP in females is higher than that in males. The value of IOP measurement itself in glaucoma screening is very limited. A combination with fundus photography is highly recommended.

Key words： intraocular pressure health examination Shenyang

Received: 18 November 2020

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Fund: Basic Scientific Research Foundation of Wenzhou (Y20190695); Key Innovation & Guidance Project of the Eye Hospital, School of Ophthalmology & Optometry, Wenzhou Medical University (YNZD2201903)

Corresponding Authors: Shaodan Zhang, Eye Hospital, Wenzhou Medical University, National Clinical Research Center for Ocular Diseases, Glaucoma Research Institute of Wenzhou Medical University, Wenzhou 325027, China (Email: shaodan_zhang_wmu@126.com)

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https://www.cjoovs.com/EN/10.3760/cma.j.cn115909-20201118-00445 OR https://www.cjoovs.com/EN/Y2021/V23/I4/281

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