青年近视人群视网膜劈裂的OCT特征

doi:10.3760/cma.j.cn115909-20210210-00058

Abstract
Figure/Table
References (20)
Related Citation (15)

Download: PDF (9031 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS) Supporting Info

Guide

Abstract Objective: To investigate the spectral domain optical coherence tomography (SD-OCT) imaging characteristics of retinoschisis by observing the types, prevalence, composition, distribution and clinical features of retinoschisis in a young myopic population. Methods: This was a cross-sectional study. A total of 1 046 eyes of 523 myopia patients who were treated at the ophthalmological laser surgery outpatient department of the Second Hospital of Hebei Medical University from July 2020 to December 2020 were recruited. Of these, 227 eyes (21.7%) were diagnosed with low myopia (-3.00- 0 D), 405 eyes (38.7%) were diagnosed with moderate myopia (>-6.00- -3.00 D), and 414 eyes (39.6%) were diagnosed with high myopia (≤-6.00 D). The participants underwent a complete ophthalmologic examination, including best corrected visual acuity, axial length measurement, refractive error, color fundus photography and SD-OCT examinations. Multiple SD-OCT scans of each patient were made along the upper and lower arcades of the temporal and nasal quadrants of the retina and across the fovea. The distribution of retinoschisis in the four quadrants of the retina was observed. The types, prevalence, composition, distribution and clinical features of retinoschisis were analyzed. A Pearson Chi-square test was used for statistical analysis of the distribution of paravascular inner and outer retinoschisis. Fisher's exact test was used for statistical analysis of the distribution of middle retinoschisis. The Kruskal-Wallis rank sum test was used for statistical analysis of age and refractive error in the subgroups of paravascular retinoschisis. ANOVA was used for statistical analysis of axial length. Results: Of the 1 046 eyes with different degrees of myopia, paravascular retinoschisis was detected by SD-OCT in 30 eyes (2.9%). Myopic macular retinoschisis was never detected. Paravascular retinoschisis was classified into three different subtypes: Inner, middle and outer retinoschisis. The overall prevalence of the three subtypes of paravascular retinoschisis in the young myopic population was 2.9%, 0.8% and 1.5%, respectively. Of the 30 eyes with paravascular retinoschisis, inner retinoschisis was found in all 30 eyes, middle retinoschisis in 8 eyes, and outer retinoschisis in 16 eyes. All three subtypes of paravascular retinoschisis (inner: χ2 =13.468, P<0.001, middle: P=0.002, outer: χ2 =13.576, P<0.001) were observed more frequently along the temporal vascular arcades. Conclusions: All three subtypes of paravascular retinoschisis were more frequently observed along the temporal vascular arcades. Inner retinoschisis may be the predominant subtype of paravascular retinoschisis and is mainly related to the tangential traction of the posterior vitreous cortical and anterior traction of the retinal vessels in a young myopic population.

Key words： paravascular retinoschisis spectral domain optical coherence tomography young population myopia

Received: 10 February 2021

PACS:

Fund:

Corresponding Authors: Yuhua Hao, Department of Ophthalmology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China (Email: yuhuasjz@sina.com)

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors

Cite this article:

URL:

https://www.cjoovs.com/EN/10.3760/cma.j.cn115909-20210210-00058 OR https://www.cjoovs.com/EN/Y2021/V23/I8/576

[1]	Xiao W, Zhu Z, Odouard C, et al. Wide-field enface swept-source optical coherence tomography features of extrafoveal retinoschisis in highly myopic eye. Invest Ophthalmol Vis Sci, 2017, 58(2): 1037-1044. DOI: 10.1167/iovs.16-20607.
[2]	Kamal-Salah R, Morillo-Sanchez MJ, Rius-Diaz F, et al. Relationship between paravascular abnormalities and foveoschisis in highly myopic patients. Eye (Lond), 2015, 29(2): 280-285. DOI: 10.1038/eye.2014.255.
[3]	Kobayashi K, Ohno-Matsui K, Kojima A, et al. Fundus characteristics of high myopia in children. Jpn J Ophthalmol, 2005, 49(4): 306-311. DOI: 10.1007/s10384-004-0204-6.
[4]	Sun CB, You YS, Liu Z, et al.Myopic macular retinoschisis in teenagers: Clinical characteristics and spectral domain optical coherence tomography findings. Sci Rep, 2016, 6(1): 27952. DOI: 10.1038/srep27952.
[5]	Shimada N, Ohno-Matsui K, Nishimuta A, et al. Detection of paravascular lamellar holes and other paravascular abnormalities by optical coherence tomography in eyes with high myopia. Ophthalmology, 2008, 115(4): 708-717. DOI: 10.1016/j.ophtha. 2007.04.060.
[6]	Li T, Wang X, Zhou Y, et al. Paravascular abnormalities observed by spectral domain optical coherence tomography are risk factors for retinoschisis in eyes with high myopia. Acta Ophthalmol, 2018, 96(4): e515-e523. DOI: 10.1111/aos.13628.
[7]	Baba T, Ohno-Matsui K, Futagami S, et al. Prevalence and characteristics of foveal retinal detachment without macular hole in high myopia. Am J Ophthalmol, 2003, 135(3): 338-342. DOI: 10.1016/s0002-9394(02)01937-2.
[8]	Curtin BJ. The posterior staphyloma of pathologic myopia. Trans Am Ophthalmol Soc, 1977, 75: 67-86.
[9]	Ohno-Matsui K. Proposed classification of posterior staphylomas based on analyses of eye shape by three-dimensional magnetic resonance imaging and wide-field fundus imaging. Ophthalmology, 2014, 121(9): 1798-1809. DOI: 10.1016/ j.ophtha.2014.03.035.
[10]	Fujimoto M, Hangai M, Suda K, et al. Features associated with foveal retinal detachment in myopic macular retinoschisis. Am J Ophthalmol, 2010, 150(6): 863-870. DOI: 10.1016/ j.ajo.2010.06.023.
[11]	Tang J, Rivers MB, Moshfeghi AA, et al. Pathology of macular foveoschisis associated with degenerative myopia. J Ophthalmol, 2010, 2010: 1-4. DOI: 10.1155/2010/175613.
[12]	Shinohara K, Tanaka N, Jonas JB, et al. Ultrawide-field OCT to investigate relationships between myopic macular retinoschisis and posterior staphyloma. Ophthalmology, 2018, 125(10): 1575- 1586. DOI: 10.1016/j.ophtha.2018.03.053.
[13]	Song ML, Shen MX, Zhou YP, et al. Observation of vitreous features using enhanced vitreous imaging optical coherence tomography in highly myopic retinoschisis. Retina, 2019, 39(9): 1732-1741. DOI: 10.1097/IAE.0000000000002226.
[14]	Johnson MW. Myopic traction maculopathy: pathogenic mechanisms and surgical treatment.Retina, 2012, 32(suppl 2): S205-S210. DOI: 10.1097/IAE.0b013e31825bc0de.
[15]	Takano M, Kishi S. Foveal retinoschisis and retinal detachment in severely myopic eyes with posterior staphyloma. Am J Ophthalmol, 1999, 128(4): 472-476. DOI: 10.1016/s00029394 (99)00186-5.
[16]	Henaine-Berra A, Zand-Hadas IM, Fromow-Guerra J, et al. Prevalence of macular anatomic abnormalities in high myopia. Ophthalmic Surg Lasers Imaging Retina, 2013, 44(2): 140-144. DOI: 10.3928/23258160-20130219-01.
[17]	王克岩, 徐格致, 吕嘉华, 等. 高度近视眼底后部血管弓旁视网膜改变的频域光学相干断层扫描特征. 中华眼视光学与视觉科学杂志, 2013, 15(7): 418-422. DOI: 10.3760/cma. j.issn.1674-845X.2013.07.009.
[18]	Cheng C, Teo K, Tan CS, et al. Myopic retinoschisis in Asians structural features and determinants of visual acuity and prognostic factors for progression. Retina, 2016, 36(4): 717-726. DOI: 10.1097/IAE.0000000000000757.
[19]	Gaudric A. Macular cysts, holes and cavitations: 2006 Jules Gonin lecture of the retina research foundation. Graefes Arch Clin Exp Ophthalmol, 2008, 246(7): 1071-1079. DOI: 10.1007/ s00417-008-0818-3.
[20]	Ichibe M, Baba E, Funaki S, et al. Retinoschisis in a highly myopic eye without vision impairment. Retina, 2004, 24(2): 331-333. DOI: 10.1097/00006982-200404000-00033.

[1]	. [J]. Chinese Journal of Optometry Ophthalmology and Visual science, 2023, 25(8): 0-.