OCTA观察高度近视眼ICL植入术后视网膜血流密度的变化

doi:10.3760/cma.j.cn115909-20210506-00183

Abstract
Figure/Table
References (24)
Related Citation (15)

Download: PDF (767 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS) Supporting Info

Guide

Abstract

Objective: To observe the effect of posterior chamber intraocular lens (ICL) implantation on retinal

blood flow density and retinal thickness in high myopia using optical coherence tomography angiography

(OCTA). Methods: This was a prospective clinical study. Twenty-five patients (43 eyes) who underwent

ICL implantation from December 2019 to may 2020 in the Affiliated Eye Hospital of Nanjing Medical

University were selected. The spherical equivalent (SE) was >-6.00 D. Visual acuity, intraocular pressure,

arch height, macular blood flow density and retinal thickness were measured before the operation and

1 week, 1 month and 3 months after the operation. The data were analyzed with repeated measures ANOVA.visual acuity (BCVA, LogMAR) were statistically significant (F=500.975, P<0.001; F=16.032, P<0.001,

respectively), and all improved compared to the preoperative values (P<0.001). The macular foveal

retinal thickness (CRT) did not change significantly after surgery, but the area of the avascular zone (FAZ)

decreased significantly after surgery (all P<0.001), and difference between preoperative and postoperative

were statistically significant (P<0.001), respectively. There was no significant difference in superficial

retinal blood flow density in the fovea, parafovea, temporal, superior, nasal or inferior regions before the

operation, and 1 week, 1 month and 3 months after the operation. There was no significant difference in

the deep retinal blood flow density in the fovea, temporal, superior or inferior regions 1 week, 1 month

and 3 months after the operation, but the deep retinal blood flow density in the parafovea and nasal region

decreased after the operation (all P<0.05). Conclusions: According to the OCTA, ICL implantation has a

significant effect on deep nasal retinal blood flow density, and decreases the area of FAZ, however there is

no significant effect on other retinal blood flow and thickness parameters.

Results: The postoperative uncorrected visual acuity (UDVA, LogMAR) and postoperative best corrected

Key words： optical coherence tomography angiography implantable collamer lens retinal blood flow density high myopia

Received: 06 May 2021

PACS:

Fund:

National Natural Science Foundation of China (81970823)

Corresponding Authors: Xiangzhong Xu, the Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210029, China (Email: 25068411@qq.com)

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	Yingnan Xu
	Jin Yao
	Tan Long
	et al

Cite this article:

Yingnan Xu,Jin Yao,Tan Long等. Changes in Retinal Blood Flow Density after ICL Implantation in High Myopia Using Optical Coherence Tomography Angiography[J]. Chinese Journal of Optometry Ophthalmology and Visual science, 2021, 23(12): 881-886.

URL:

https://www.cjoovs.com/EN/ 10.3760/cma.j.cn115909-20210506-00183 OR https://www.cjoovs.com/EN/Y2021/V23/I12/881

[1]	王红霞, 彭艳丽, 赵中秀, 等. 有晶状体眼人工晶状体后房方位与拱高的相关性. 中华眼视光学与视觉科学杂志, 2020,22(10): 738-743. DOI: 10.3760/cma.j.cn115909-20200401-00127.
[2]	Fernández-Vega-Cueto L, Lisa C, Esteve-Taboada JJ, et al.Implantable collamer lens with central hole: 3-year follow-up.Clin Ophthalmol, 2018, 12: 2015-2029. DOI: 10.2147/OPTH.S171576.
[3]	Shimizu K, Kamiya K, Igarashi A, et al. Long-term comparisonof posterior chamber phakic intraocular lens with and without a central hole (Hole ICL and Conventional ICL) implantation for moderate to high myopia and myopic astigmatism: consortcompliant article. Medicine,2016, 95(14): e3270. DOI: 10.1097/MD.0000000000003270.
[4]	Chen M, Dai J, Gong L. Changes in retinal vasculature andthickness after small incision lenticule extraction with optical coherence tomography angiography. J Ophthalmol, 2019, 2019:3693140. DOI: 10.1155/2019/3693140.
[5]	Zhou TA, Jiang H, Wang Y, et al. Comparison of anteriorchamber angle changes following phakic intraocular lens with and without a central hole implantation for moderate to high myopic eyes. Medicine (Baltimore), 2020, 99(49): e23434. DOI:10.1097/MD.0000000000023434.
[6]	Li M, Yang Y, Jiang H, et al. Retinal microvascular network andmicrocirculation assessments in high myopia. Am J Ophthalmol,2017, 174:56-67. DOI: 10.1016/j.ajo.2016.10.018.
[7]	Li T, Guadie A, Feng L, et al. Influence of cataract surgery onmacular vascular density in patients with myopia using optical coherence tomography angiography. Exp Ther Med, 2020,20(6): 258. DOI: 10.3892/etm.2020.9388.
[8]	中华医学会眼科学分会眼视光学组. 中国有晶状体眼后房型人工晶状体植入术专家共识(2019 年). 中华眼科杂志, 2019,55(9): 652-657. DOI: 10.3760/cma.j.issn.0412-4081.2019.09.005.
[9]	Kim BK, Chung YT. Comparison of clinical outcomes ofimplantable collamer lens implantation with and without use of an ophthalmic viscosurgical device. J Cataract Refract Surg,2021, 47(2): 198-203. DOI: 10.1097/j.jcrs.0000000000000417.
[10]	Fujisawa K, Shimizu K, Uga S, et al. Changes in the crystallinelens resulting from insertion of a phakic IOL (ICL) into the porcine eye. Graefes Arch Clin Exp Ophthalmol, 2007, 245(1):114-122. DOI: 10.1007/s00417-006-0338-y.
[11]	Almalki S, Abubaker A, Alsabaani NA. et al. Causes of elevatedintraocular pressure following implantation of phakic intraocular lenses for myopia. Int Ophthalmol, 2016, 36(2): 259-265. DOI:10.1007/s10792-015-0112-4.
[12]	罗金香, 肖满意, 段宣初. OCTA在评估高度近视眼底形态及血流变化中应用的研究进展. 中华眼视光学与视觉科学杂志, 2020, 22(10): 789-795. DOI: 10.3760/cma.j.cn115909-20200420-00157.
[13]	Kashani AH, Chen CL, Gahm JK, et al. Optical coherencetomography angiography: a comprehensive review of current methods and clinical applications. Prog Retin Eye Res, 2017,60: 66-100. DOI: 10.1016/j.preteyeres.2017.07.002.
[14]	Zhu QJ, Wang MY, Yu P, et al. Analysis of macularmicrovasculature and thickness after ICL implantation in patients with myopia using optical coherence tomography. Int J Ophthalmol, 2020, 13(12): 1948-1954. DOI: 10.18240/ijo.2020.12.16.
[15]	Ozgur OR, Ozkurt Y, Kulekci Z, et al. The combination ofphacoemulsification surgery and intravitreal triamcinolone injection in patients with cataract and diabetic macular edema.Saudi J Ophthalmol, 2016, 30(1): 33-38. DOI: 10.1016/j.sjopt.2015.10.004.
[16]	吴姜雪, 王剑锋, 许澈. 糖尿病患者行白内障超声乳化术后黄斑水肿的发生率及危险因素. 临床医学进展, 2020, 10(3):460-466. DOI: 10.12677/ACM.2020.103072.
[17]	Kamiya K, Shimizu K, Igarashi A, et al. Clinical outcomesand patient satisfaction after Visian Implantable Collamer Lens removal and phacoemulsification with intraocular lens implantation in eyes with induced cataract. Eye (Lond), 2010,24(2): 304-309. DOI:10.1038/eye.2009.87.
[18]	Carpineto P, Mastropasqua R, Marchini G, et al. Reproducibilityand repeatability of foveal avascular zone measurements in healthy subjects by optical coherence tomography angiography.Br J Ophthalmol, 2016, 100(5): 671-676. DOI: 10.1136/bjophthalmol-2015-307330.
[19]	刘俊, 廖荣丰. 基于OCTA的白内障超声乳化术后黄斑区视网膜厚度和血管密度分析. 眼科新进展, 2020, 40(4): 377-380.DOI: 10.13389/j.cnki.rao.2020.0087.
[20]	Springer AD, Hendrickson AE. Development of the primate areaof high acuity, 3: temporal relationships between pit formation,retinal elongation and cone packing. Vis Neurosci, 2005, 22(2):171-185. DOI: 10.1017/S095252380522206X.
[21]	Wons J, Pfau M, Wirth MA, et al. Optical coherence tomographyangiography of the foveal avascular zone in retinal vein occlusion. Ophthalmologica, 2016, 235(4): 195-202. DOI:10.1159/000445482.
[22]	Balaratnasingam C, Inoue M, Ahn S, et al. Visual acuity iscorrelated with the area of the foveal avascular zone in diabetic retinopathy and retinal vein occlusion. Ophthalmology, 2016,123(11): 2352-2367. DOI: 10.1016/j.ophtha.2016.07.008.
[23]	Alshareef RA, Khuthaila MK, Januwada M, et al. Choroidalvascular analysis in myopic eyes: evidence of foveal medium vessel layer thinning. Int J Retina Vitreous, 2017, 3: 28. DOI:10.1186/s40942-017-0081-z.
[24]	Baudouin C, Kolko M, Melik-Parsadaniantz S, et al.Inflammation in glaucoma: from the back to the front of the eye, and beyond. Prog Retin Eye Res, 2021, 83: 100916. DOI:10.1016/j.preteyeres.2020.100916.

[1]

Chinese Optometric Association, Chinese Ophthalmological Society; Ophthalmology and Optometry Committee, Ophthalmologists Association, Chinese Doctor Association; et al. Expert Consensus on Prevention and Control of High Myopia (2023)[J]. Chinese Journal of Optometry Ophthalmology and Visual science, 2023, 25(6): 401-407.