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Research Progress on Corneal Collagen Cross-Linking and Its Combination with Refractive Surgery for Keratoconus |
Yanting Chen, Xiaohan Liu, Ning Ma, Yueguo Chen |
Department of Ophthalmology, Peking University Third Hospital, Beijing 100191, China |
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Guide |
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Abstract Corneal collagen cross-linking (CXL) has become the preferred modality of treatment for progressive
keratoconus since the late 1990s. There has been an increasing appeal for a completely surgical approach by
combining CXL with adjuvant refractive procedures both to halt the ectatic process and enhance functional
visual outcomes. Several combined protocols have been studied to various degrees in conjunction with
CXL, involving photorefractive keratectomy, transepithelial phototherapeutic keratectomy, intrastromal
corneal ring segments implantation, and phakic intraocular lens implantation. This review summarizes
current CXL protocols, presents the current status of studies involving CXL plus and discusses the future
potential of these protocols.
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Received: 03 August 2020
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Fund:Key Clinical Innovation Program of Peking University Third Hospital, Category A (Y65495-05) |
Corresponding Authors:
Yueguo Chen, Department of Ophthalmology, Peking University Third Hospital, Beijing
100191, China (Email: chenyueguo@263.net)
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