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Clinical Study of Ocular Acupuncture Therapy for Dry Eye due to the Deficiency of Qi and Yin |
Lei Zhao1, Kaiyao Chi2, Huimin Zhou2, Tao Zuo1 |
Liaoning University of TCM, Shenyang 110032, China 2 The Second Affiliated Hospital of Liaoning University of TCM, Shenyang 110034, China |
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Guide |
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Abstract Objective: Observing the clinical efficacy of ocular acupuncture in the treatment of dry eye due to the deficiency of Qi and Yin, and to explore its mechanism. Methods: In this prospective study, 74 patients with dry eye due to the deficiency of Qi and Yin from the Second Affiliated Hospital of Liaoning University of TCM were recruited from January to April 2021. Seventy-four patients were randomly divided into an ocular acupuncture group and a conventional acupuncture group, 37 patients in each group. The conventional acupuncture group was treated with conventional acupuncture; the ocular acupuncture therapy group received ocular acupuncture therapy, and 4 acupoints were taken from the liver, lung, spleen and kidney regions. The course of treatment was 14 days. The ocular surface disease index (OSDI) score before and after treatment was recorded. The Schirmer Ⅰ test (SⅠT) and corneal fluorescein staining (CFS) were used for assessment. The non-invasive first tear film break-up (NIBUTf) and non-invasive average tear film break-up (NIBUTav)were measured by the K5M ocular surface analyzer. Data were analyzed by the t test, Wilcoxon test and Chi-square test. Results: The OSDI score, S Ⅰ T, NIBUTf, NIBUTav and CFS of the two groups were significantly different before and after treatment (P<0.05). After treatment, the OSDI score, S Ⅰ T, NIBUTf, and NIBUTav of the two groups were significantly different (P<0.05). There was no significant difference in CFS between the two groups after treatment. Conclusion: Both ocular acupuncture and conventional acupuncture can effectively treat dry eye due to the deficiency of Qi and Yin. Ocular acupuncture is superior to conventional acupuncture in improving ocular surface symptoms, tear secretion and tear film rupture time of dry eye patients, with a higher efficacy and compliance.
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Received: 11 June 2021
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Fund:Evidence-Based Capacity Building Project of Traditional Chinese Medicine of State Administration of Traditional Chinese Medicine |
Corresponding Authors:
Tao Zuo, the Second Affiliated Hospital of Liaoning University of TCM, Shenyang 110034, China (Email: ykzt208@163. com)
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[1] |
亚洲干眼协会中国分会, 海峡两岸医药卫生交流协会眼科 学专业委员会眼表与泪液病学组, 中国医师协会眼科医师 分会眼表与干眼学组. 中国干眼专家共识: 定义和分类(2020 年). 中华眼科杂志, 2020, 56(6): 418-422. DOI: 10.3760/cma. j.cn112142-20200316-00190.
|
[2] |
严丹, 严晨曦, 傅瑶. 泪膜与眼表微环境的研究进展.中华眼 视光学与视觉科学杂志, 2019, 21(11): 877-880. DOI: 10.3760/ cma.j.issn.1674-845X.2019.11.015.
|
[3] |
王杨 , 黄钰清 , 杨燕宁 . 地夸磷索钠滴眼液对中重度干 眼 患 者 眼 表 状 况 和 视 觉 质 量 的 影 响 . 中 华 眼 视 光 学 与 视觉科学杂志, 2021, 23(5): 329-335. DOI: 10.3760/cma. j.cn115909-20201029-00418.
|
[4] |
孙旭光. 解读国际泪膜与眼表协会2017 年干眼专家共识中 的性别及性激素与干眼. 中华眼科杂志, 2018, 54(2): 90-92. DOI: 10.3760/cma.j.issn.0412-4081.2018.02.004.
|
[5] |
彭筱山, 王鹏琴, 彭静山. 眼针疗法. 沈阳: 辽宁科学技术出版 社, 2018: 9.
|
[6] |
亚洲干眼协会中国分会, 海峡两岸医药卫生交流协会眼科 学专业委员会眼表与泪液病学组, 中国医师协会眼科医师 分会眼表与干眼学组. 中国干眼专家共识: 检查和诊断(2020 年). 中华眼科杂志, 2020, 56(10): 741-747. DOI: 10.3760/cma. j.cn112142-20200714-00477.
|
[7] |
彭清华. 中医眼科学. 普通高等教育中医药类“十三五”规划 教材, 上海: 上海科学技术出版社, 2019: 128.
|
[8] |
Bron AJ, Smith JA, Calonge M. Methodologies to diagnose and monitor dry eye disease: report of the diagnostic methodology Subcommittee of the International Dry Eye WorkShop (2007). Ocular Surface, 2007, 5(2): 108-152. DOI: 10.1016/S1542- 0124(12)70083-6.
|
[9] |
中华医学会眼科学分会角膜病学组. 干眼临床诊疗专家共识 (2013年). 中华眼科杂志, 2013, 49(1): 73-75. DOI: 10.3760/ cma.j.issn.0412-4081.2013.01.020.
|
[10] |
Craig JP, Nelson JD, Azar DT, et al. TFOS DEWS II Report executive summary. Ocul Surf, 2017, 15(4): 802-812. DOI: 10.1016/j.jtos.2017.08.003.
|
[11] |
赵磊, 李晓静, 王方媛, 等. 基于气与津液相互关系论干眼. 中 国中医眼科杂志, 2020, 30(12): 888-890. DOI: 10.13444/j.cnki. zgzyykzz.2020.12.011.
|
[12] |
赵越, 黄琴峰, 智方圆, 等. 五官科针灸疾病谱现代文献计 量分析与评价. 上海针灸杂志, 2018, 37(1): 112 -117. DOI: 10.13460/j.issn.1005-0957.2018.01.0112.
|
[13] |
Na JH, Jung JH, Park JG, et al. Therapeutic effects of acupuncture in typical dry eye: a systematic review and meta- analysis. Acta Ophthalmol, 2021, 99(5): 489-498. DOI: 10.1111/ aos.14651.
|
[14] |
浦延鹏, 王鹏琴. 眼针止痛, 从络论治. 辽宁中医杂志, 2020, 47(9): 147-149. DOI: 10.13192/j.issn.1000-1719.2020.09.045.
|
[15] |
袁双双, 崔韶阳, 刘露阳, 等. 眼针疗法治疗急性腰痛的随机 对照研究. 针灸临床杂志, 2020, 36(11): 10-13. DOI: 10.3969/ j.issn.1005-0779.2020.11.004.
|
[16] |
王娜莎. 眼针配合通窍活血汤加减治疗瘀血型偏头痛疗效 观察. 西部中医药, 2020, 33(03): 111-113. DOI: 10.12174/ j.issn.1004-6852.2020.03.31.
|
[17] |
程修平, 王鹏琴. 眼针联合治疗中风后抑郁疗效Meta分析. 辽宁中医药大学学报, 2019, 21(6): 113-116. DOI: 10.13194/ j.issn.1673-842x.2019.06.030.
|
[18] |
晏晓明. 解读国际泪膜与眼表协会2017 年干眼专家共识中 的干眼流行病学. 中华实验眼科杂志, 2019, 37(3): 226-228. DOI: 10.3760/cma.j.issn.2095-0160.2019.03.013.
|
[19] |
王路, 王德山, 刘旭东, 等. 眼针对抑郁模型大鼠海马及下丘 脑五羟色胺表达的影响. 中华中医药学刊, 2014, 32(5): 990- 992. DOI: 10.13193/j.issn.1673-7717.2014.05.008.
|
[20] |
刘 光 辉 , 白 丽 , 王 恩 龙 , 等 . 眼 针 治 疗 失 眠 随 机 对 照 试 验 的 系 统 评 价 和 M e t a 分 析 . 中 西 医 结 合 心 脑 血 管病杂志, 2018, 16(17): 2457-2465. DOI: 10.12102/ j.issn.1672-1349.2018.17.005.
|
[21] |
李柯然, 李苛苛, 童楠, 等. 非侵入式眼表分析仪评价儿童 异常瞬目症与干眼的相关性 . 中华眼视光学与视觉科学 杂志, 2019, 21(8): 630-635. DOI: 10.3760/cma.j.issn.1674- 845X.2019.08.013.
|
[22] |
程娟, 李琦, 任丽红, 等. 眼针联合常规针刺治疗肝肾阴 虚型干眼临床观察. 中国针灸, 2019, 39(9): 945-949. DOI: 10.13703/j.0255-2930.2019.09.008.
|
[23] |
冯督. 自拟清肺地黄汤联合眼针治疗干眼症患者的疗效分析. 实用中西医结合临床, 2019, 19(5): 58-59, 109. DOI: 10.13638/ j.issn.1671-4040.2019.05.029.
|
|
|
|