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| Characteristics and Correlation of Diopter and Eyeball Biological Parameters in Term Neonates |
| Xinli Liu, Lihua Wang, Wei Chen |
| Department of Ophthalmology, Haidian Maternal and Child Health Hospital, Beijing 100080, China |
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Abstract Objective: To investigate the characteristics of diopter and ocular biological parameters in term neonates, and to analyze the correlation between diopter and ocular biological parameters. Methods: In this cross-sectional study, a total of 71 full-term neonates (142 eyes) born in Haidian Maternal and Child Health Hospital were included and examined within 7 days of birth with the method of simple random sampling. The diopter was obtained by retinoscopy after cycloplegia, the depth of the anterior chamber (ACD), the lens thickness the depth of the vitreous cavity (V) and the axial length (AL) were obtained by measuring the eyeA-type ultrasound, and the keratometric power of the cornea (Km) was obtained by a handheld computer refractometer. The corneal curvature radius (CR) was calculated from Km. The axial ratio (AL/CR) was calculated fromAL and CR. The lens refractive power (LP) were calculated fromAL,ACD,Km, spherical equivalent (SE). Spearman correlation analysis and linear regression were used to analyze the relationship between diopter, axial length, lens diopter and other parameters. Results: SE of these infants was +3.00 (+2.00, +5.25)D, Km was 46.25 (44.63, 47.63)D, AL was (16.99±0.49)mm, LP was (46.10±5.13)D. SE showed a negative correlation with AL and LP (r=-0.52, P<0.001; r=-0.21, P=0.014), but not with Km (r=-0.16, P=0.053). ALwas positively correlated with gestational age (GA) (r=0.24,P=0.005). Regression analysis demonstrated that AL=11.937+0.129×GA(R2=0.07, F=10.75, P=0.001),SE=60.362-2.835×AL-0.190×LP(R2=0.39, F=44.95, P<0.001). Conclusions:The refractive status of full-term neonates is moderate to high hyperopia, with shorter AL and larger LP than adutls. SE is negatively correlated withAL, but not with KM,AL is a key factor affecting SE.
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Received: 08 June 2022
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| Fund:Health Development Scientific Research Cultivation Program of Beijing Haidian District (HP2022-10-103004) |
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Corresponding Authors:
Wei Chen, Department of Ophthalmology, Haidian Maternal and Child Health Hospital, Beijing 100080, China (Email: chenweidgj@163.com)
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