活体共聚焦显微镜在干眼患者眼表形态观察中的应用

doi:10.3760/cma.j.issn.1674-845X.2014.09.015

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Abstract

Dry eye syndrome is one of the most common ocular disorders. Although significant advances in both basic and clinical research have been made over the past years， the pathophysiological mechanisms of dry eye syndrome still need further clarification. In vivo confocal microscopy is a noninvasive ocular imaging tool that allows the observation of ocular surface epithelial cells， immune and inflammatory cells， corneal nerves， keratocytes， and meibomian gland structures on a cellular level. Therefore， it could help improve understanding of the pathogenesis and pathophysiology of the dry eye syndrome. Ocular surface structures in dry eye-related conditions could be assessed and alterations could be quantified using in vivo confocal microscopy， and it may enable the disease to be detected at much earlier stages and allow stratification of patients for clinical therapies. Furthermore， dynamic observation of the changes in confocal images could also help monitor the efficacy of treatment strategies， thus tailoring treatment in a timely manner and evaluating the prognoses more accurately.

Key words： Dry eye syndrome Microscopy confocal Ocular surface Meibomian gland

Received: 07 June 2014

Corresponding Authors: Li Ying，Email：liyingpumch@sohu.com

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Cite this article:

Yu Chenying,Li Ying. Application of in vivo confocal microscopy to observe ocular surface morphology in dry eye patients[J]. Chinese Journal of Optometry Ophthalmology and Visual science, 2014, 16(9): 573-576.

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https://www.cjoovs.com/EN/10.3760/cma.j.issn.1674-845X.2014.09.015 OR https://www.cjoovs.com/EN/Y2014/V16/I9/573

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