Abstract Objective To summarize and analyze the ocular conditions of patients with myasthenia gravis (MG) diagnosed in the MG therapy center and those who came for ocular consultation in our department.Methods In a retrospective case study,181 patients with MG who came for ocular consultation from January 2009 to August 2011 were analyzed,and underwent the following examinations:visual acuity,slit lamp microscope examination,fundus examination,refractive condition,eye alignment at 33 cm and 6 m,eye movement,and diplopic images by the red glass test.Some patients were also examined with a synoptophore.Data was categorized,collected and analyzed.Results Of those 181 cases,many patients were diagnosed with ocular MG (86,47.5%),150 cases had normal eye alignment (82.9%),175 cases had eyelid ptosis (96.7%),5 cases had monocular amblyopia (2.8%),and 156 patients had diplopia (86.2%).Of those 181 cases,55 patients (30.4%) had paralysis of one simple ocular muscle,77 cases (42.5%) had paralysis of multiple ocular muscles,and 13 patients (7.2%) had paralysis of all ocular muscles.Of those 55 patients with paralysis of one simple ocular muscle,most had involvement of the medial rectus (14,25.5%).Conclusion Almost half of the former patients with MG who came for ocular consultation were diagnosed with ocular MG.In patients with MG,most had eyelid ptosis and diplopia.However,most patients had normal eye alignment.The patients who developed MG early had form deprivation amblyopia because of eyelid ptosis.Paralysis of ocular muscles can involve one simple muscle,multiple muscles or all muscles,and most patients had a paralysis of multiple muscles or one simple muscle.In patients with paralysis of one simple ocular muscle,the medial rectus muscle was most often involved.
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