Objective To compare the efficacy of using of FP-7 and S2 Ahmed glaucoma valve implantations （AGI） for refractory glaucoma and to monitor postoperative complications. Methods A retrospective study was conducted to document patients with refractory glaucoma who underwent S2 （26 eyes from 26 patients） or FP-7 （23 eyes from 23 patients） AGI in the Center Hospital of Cangzhou. The change in IOP， the surgical success rate， and postoperative complications were recorded and analyzed. A variance analysis of repeated measurement data was used for comparison of preoperative and postoperative IOP and the effect of reducing IOP in the 2 observation groups. Cumulative survival rates were calculated using survival analysis and compared using a log-rank. The Fisher exact test was used for the comparison of complication rates. Results IOP was reduced from 38.19±10.56 mmHg to 14.54±4.11， 15.83±5.76， 17.19±4.96， and 18.84±5.28 mmHg at month 1， month 6， month 12， and month 24 postoperatively in the S2 group and reduced from 39.91±9.12 mmHg to 14.41±5.14， 15.95±4.32， 17.11±4.75， and 19.06±6.55 mmHg in the FP-7 group. There was no statistically significant difference between the 2 groups for their effect on lowering IOP. At the last follow-up， the cumulative probabilities of success and of total success were 82% and 74% in the S2 group， and 80% and 75% in the FP-7 group. There was no statistically significant difference between the 2 groups. Conclusion FP-7 AGI was equal to S2 AGI in reducing IOP in refractory glaucoma. The complication rate in the S2 group was no higher than it was in the FP-7 group.