|
|
Effects of low pressure hypoxia on visual function after laser in situ keratomileusis |
Zhao Rong,Yin Dongchen,Wang Enpu,Zhang Xiangran,Zhao Ruihua,Wang Jianchang |
Air Force General Hospital, PLA, Beijing 100142, China |
|
|
Abstract Objective To test the effects of altitude hypoxia on visual function after laser in situ keratomileusis (LASIK) and to evaluate flight adaptability after laser refractive surgery. Methods This was a self-control designed study. Forth eyes of 20 healthy males with a mean age of 23.8±1.2 years volunteered for this prospective study. All patients had bilateral LASIK surgery 1 year prior to the study. Interocular pressure, near stereopsis, color vision, refractive error, contrast sensitivity (CS) (photopic, scotopic+glare environments; 3, 6, 12, 18 c/d spatial frequencies) were measured before exposure to the hypobaric chamber. The atmosphere in the chamber ascended to an equivalent of a 5 000 m altitude at the rate of 30 m/s. Subjects were measured again after remaining there for 10 minutes without an oxygen supply. The chamber then returned to ground level at the rate of 10-15 m/s. Data were analyzed using a paired t test. Results There were no significant differences in intraocular pressure or spherical equivalent refractive error for either eye before and after the hypobaric experiment: right eyes: 13.0±1.7 mmHg vs. 13.0±2.1 mmHg, t=-0.56, P>0.05, -0.90±0.61 D vs. -1.08±0.75 D, t=1.71, P>0.05; left eyes: 13.0±2.0 mmHg vs. 13.0±2.0 mmHg, t=-0.81, P>0.05; -1.21±0.61 D vs. -1.06±0.54 D, t=-1.33, P>0.05). Near stereopsis (21.5±2.4 vs. 27.6±8.3, t=-3.39, P<0.05) and color vision (9.60±2.73 vs. 27.20±8.57, t=-2.81, P<0.05) were depressed. Contrast sensitivity was depressed only at 18 cycles/degree in the scotopic+glare environment. Conclusion Based on this study, we conclude that hypoxia has little effect on interocular pressure, refractive error or CS except at 18 c/d in the scotopic+glare environment after LASIK surgery. Near stereopsis, color vision and CS at 18 c/d in the scotopic+glare environment were reduced.
|
Received: 20 May 2014
|
Corresponding Authors:
Wang Jianchang, Email: kzdw66@sohu.com
|
|
|
|
[1] |
赵蓉,肖华军,王恩普,等. 高空缺氧和迅速减压对准分子激光原位角膜磨镶术后兔角膜瓣稳定性的影响[J]. 中华眼视光学与视觉科学杂志,2013,15:362-364.
|
[2] |
肖华军. 航空供氧防护装备生理学[M]. 北京:军事医学科学出版社,2005:318.
|
[3] |
Aaron M, Wright S, Gooch J, et al. Stability of laser-assisted in situ keratomileusis (LASIK) at altitude[J]. Aviat Space Environ Med,2012,83:958-961.
|
[4] |
Nordan LT, Slade SG, Baker RN, et al. Femtosecond laser flap creation for laser in situ keratomileusis[J]. J Refract Surg,2003, 19:8-14.
|
[5] |
Jonas JB, Vossmerbaeumer U. Femtosecond laser LASIK flap preparation with conical incision and positional spikes[J]. J Cataract Refract Surg,2004,30:1107-1108.
|
[6] |
Reilly CD, Panday V. Advanced femtosecond LASIK: the Air Force experience[J]. Aviat Space Environ Med,2010,81:281-282.
|
[7] |
Aaron M, Gooch J, Harvey R, et al. Effect of high altitude on laser assisted in situ keratomileusis (LASIK) eyes[J]. Aviat Space Environ Med,2010,81:282.
|
[8] |
Tanzer DJ, Hofmeister E, Brunstetter T, et al. LASIK in designated naval aviators: clinical and quality-of-vision results from a prospective study[J]. Aviat Space Environ Med,2011, 82:311-312.
|
[9] |
张勇,周锡江,金玲,等. 军事飞行员屈光性角膜手术后飞行二例[J]. 中华航空航天医学杂志,2010,21:297.
|
[10] |
赵蓉,王恩普,李丹,等. 歼击机飞行人员屈光不正构成变化的研究[J]. 空军总医院学报,2008,24:70-72.
|
|
|
|