准分子激光角膜上皮瓣下磨镶术联合紫外线核黄素角膜交联术在圆锥角膜中的应用

doi:10.3760/cma.j.issn.1674-845X.2015.01.009

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Abstract

Objective To evaluate the clinical outcome of epipolis LASIK （Epi-LASIK） combined with UVA/riboflavin crosslinking in patients with mild to moderate keratoconus. Methods A total of 31 eyes in 18 patients with mild to moderate keratoconus were recruited for this prospective study. Epi-LASIK was performed using the Ziemers Microkeratome and Wavelight EX500 excimer laser. UVA/riboflavin crosslinking was applied immediately after Epi-LASIK. UCVA and BCVA and corneal topography were assessed before treatment and at 1， 3， and 6 months after treatment. Results The average K value in the center of the cornea was 46.65±2.91 D before treatment， and was 42.94±3.88 D， 41.72±4.38 D and 41.99±3.84 D at 1， 3， and 6 months after treatment. Visual acuity was 0.70±0.24 before treatment， and 0.09±0.16， 0.06±0.20 and -0.06±0.03 at 1， 3， and 6 months after treatment. There was significant improvement in UCVA （F=3.39， P<0.01） and in the reduction of the K value （F=3.57， P<0.05） when measurements before treatment were compared to measurements after treatment at months 1， 3， and 6. Conclusion Epi-LASIK combined with UVA/riboflavin crosslinking is effective in improving visual acuity in mild to moderate keratoconus patients.

Key words： Keratoconus Riboflavin Ultraviolet Collagen cross-linking Keratomileusis,laser in situ

Received: 27 October 2014

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	Articles by authors
	Xu Wenwen
	Li Zhiwei
	Chang Haiyan
	Mu Guoying.

Cite this article:

Xu Wenwen,Li Zhiwei,Chang Haiyan等. The application of epipolis LASIK combined with UVA/riboflavin crosslinking for keratoconus[J]. Chinese Journal of Optometry Ophthalmology and Visual science, 2015, 17(1): 36-38.

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https://www.cjoovs.com/EN/10.3760/cma.j.issn.1674-845X.2015.01.009 OR https://www.cjoovs.com/EN/Y2015/V17/I1/36

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