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Comparison of different multifocal electroretinography systems in the evaluation of retinal function |
Xiao-fei Man,Yolanda W Y Yip,Andrew C T Fok,Jasmine W S Ngai,Timothy YY Lai |
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Abstract Objective To investigate the differences and correlation of the first order kernels (FOK) of mfERG from normal eyes recorded by the VERIS mfERG (EDI Inc) and Espion multifocal imager (Diagnosys) systems and to analyze the mfERG parameters in eyes based on recordings of the epiretinal membrane (ERM) recorded by the two systems.Methods This was a cross-sectional study.The mfERG of 25 normal eyes were recorded separately with the VERIS system using a Burian-Allen (BA) contact lens electrode,and with the Espion system using BA and DTL electrodes.The FOK were analyzed with paired t test and Pearson correlation analysis. The FOK mfERG of 19eyes with epiretinal membrane were also recorded by the VERIS and Espion systems using a BA electrode and the results were compared with Fisher's exact test.Results In normal eyes,the response densities of the N1 and P1 waveforms recorded by VERIS BA were the highest,followed by Espion BA and finally Espion DTL.The latencies of N1 and P1 waveforms recorded by VERIS BA were longer than latencies recorded by both Espion BA and Espion DTL,while there were no significant differences between Espion BA and Espion DTL. There were significant correlations in response densities and latencies of P1 waveforms between VERIS BA and Espion BA.In ERM eyes, there were more abnormalities in amplitude densities and latencies of the FOK P1 waveforms detected by VERIS BA than by Espion BA.Conclusion Both the VERIS and Espion systems can record mfERG well.There are significant correlations in response amplitudes and latencies of FOK P1 waveforms between VERIS BA and Espion BA.
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Received: 12 April 2011
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