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Five-year evaluation of laser in situ keratomileusis for myopia |
NIU Yu-kun,WANG Wei-qun,LI Yuan-dong,XU Zhe-guang,YU Rui,WANG Zhi-meng |
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Abstract Objective To evaluate long-term refractive outcomes of laser in situ keratomileusis (LASIK) for all levels of myopia. Methods This was a retrospective case series study. One hundred twenty-five eyes of 68 patients who underwent LASIK for myopia and completed over 5 years of follow-up were included in the study. Based on the preoperative spherical equivalent refraction, the eyes were divided into 2 groups. Group A eyes ranged between -0.75 and -6.00 diopters (D) (mild-to-moderate myopia). Group B eyes ranged between -6.12 and -13.25 D (severe myopia). Before and at 1 month, 6 months, 1 year and 5 years after the operation, uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), slit-lamp biomicroscopy of the anterior segment,indirect ophthalmoscopy and topography were measured. At the time of the last follow-up, all patients completed a questionnaire assessing their satisfaction with the procedure. Data were analyzed using x² test and paired t test. Results Uncorrected visual acuity ≥0.5 in groups A and B was obtained in 100% and 96% of eyes, and spherical equivalent refraction within ±1.00 D was obtained in 93% and 84% of eyes at 5 years. Spherical equivalent refraction in groups A and B was -0.021±0.65 D and -0.33±0.80 D, respectively, at five years. The differences compared with 1-year outcomes after the operation were not statistically significant. BCVA was unchanged or improved in 82% of all eyes (103/125). Overall, only 1 epithelial ingrowth and 1 free partial flap were identified as complications from LASIK. Refraction did not regress in either group between 1 and 5 years. Late-onset complications attributable to LASIK were not observed at the 5-year follow-up, and patient satisfaction with the procedure was high. Conclusion A long-term follow-up study of patients after undergoing LASIK for myopia shows it is a safe and effective procedure in correcting all levels of myopia. Complications were rare and patient satisfaction with the surgery was high. Refractive stability was maintained over the 5-year period. Late-onset complications attributable to LASIK were not noted.
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Received: 29 July 2012
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Corresponding Authors:
WANG Wei-qun
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