Abstract: To evaluate the safety, effectiveness and predictability of Q-value-guided micro-monovision
laser in situ keratomileusis (LASIK) in the treatment of myopia and presbyopia. Methods: A prospective study was performed based on 35 patients (70 eyes) with myopia and presbyopia, who underwent Q-valueguided micro-monovision LASIK in the Affiliated Hospital of Qingdao University from August 2017
to May 2018. At the 3-month postoperative visit, examinations were performed that included binocular and monocular distance and near visual acuity (logMAR), manifest refraction, contrast sensitivity (CS)and stereopsis. In addition, questionnaires of asthenopic symptoms due to near-distance work were also included for all the patients 3 months postoperatively. The data before and after surgery were analyzed using a paired t test. Results: Binocular distance best-corrected visual acuity (BCVA) was 0.01±0.06 before surgery and was -0.04±0.21 at 3 months after surgery. Thus, none of the eyes lost one line after the operation. Uncorrected visual acuity (UCVA) of the dominant eye and the non-dominant eye were -0.04±0.19 and 0.04±0.13, respectively. In all patients, near distance UCVA of the dominant eye was equal to 20/25 or above, and that of the non-dominant eye was 20/20. In addition, the difference between the actually obtained spherical equivalent (SE) and target SE was in the range of ±0.50 D and ±1.00 D for 60 eyes (86%) and 75 eyes (100%), respectively. At 3 months after surgery, CS had a significant improvement of 18.0 c/d spatial frequency under day+peripheral glare (t=-2.504, P=0.017). The spatial frequencies for day 1.5 c/d, 6.0 c/d and 18.0 c/d, day+peripheral glare 6 c/d, night 1.5 c/d and night+peripheral glare 18.0 c/d had significantly decreased compared to that before surgery (P<0.05). All other conditions were restored to preoperative levels. There was no significant difference in stereopsis before and after surgery. No patients suffered from headache, nausea, blurred reading or difficulty with nearsightedness after near-distance work at 3 months postoperatively. All patients (100%) were satisfied with the results of the operation. Conclusions: The Q-value-guided micro-monovision LASIK protocol is a safe, effective and predictable method for the treatment of myopic patients with presbyopia. Patients can obtain better binocular distance, near vision and visual function simultaneously.
Dubbelman M, Van der Heijde GL, Weeber HA. Change in shape of the aging human crystalline lens with accommodation. Vision Res, 2005, 45(1): 117-132. DOI: 10.1016/j.visres.2004.07.032.
[2]
Ostrin LA, Glasser A. Accommodation measurements in a prepresbyopic and presbyopic population. J Cataract Refract Surg, 2004, 30(7): 1435-1444. DOI: 10.1016/j.jcrs.2003.12.045.
Cheng AC, Lam DS. Monovision LASIK for pre-presbyopic and presbyopic patients. J Cataract Refract Surg, 2005, 21(4): 411-412.
[7]
Garcia-Gonzalez M, Teus MA, Hernandez-Verdejo JL. Visual outcomes of LASIK-induced monovision in myopic patients with presbyopia. Am J Ophthalmol, 2010, 150(3): 381-386. DOI: 10.1016/j.ajo.2010.03.022.
[8]
Wright KW, Guemes A, Kapadia MS, et al. Binocular function and patient satisfaction after monovision induced by myopic photorefractive keratectomy. J Cataract Refract Surg, 1999, 25(2): 177-182.
Reinstein DZ, Couch DG, Archer TJ. LASIK for hyperopic astigmatism and presbyopia using micro-monovision with the Carl Zeiss meditec mel80 platform. J Refract Surg, 2009, 25(1): 37-58. DOI: 10.3928/1081597X-20090101-07.
[11]
Reinstein DZ, Archer TJ, Gobbe M. Lasik for myopic
astigmatism and presbyopia using non-linear aspheric micromonovision with the Carl Zeiss meditec mel 80 plataorm. J Refract Surg, 2011, 27(1): 23-37. DOI: 10.3928/1081597X-20100212-04.
[12]
Reinstein DZ, Carp GI, Archer TJ, et al. LASIK for presbyopia correction in emmetropic patients using aspheric ablation profiles and a micro-monovision protocol with the Carl Zeiss meditec mel 80 and visumax. J Refract Surg, 2012, 28(8): 531-541. DOI: 10.3928/1081597X-20120723-01.
Cao ZY, Xia LK, Lu Y, et al. Postoperative visual outcomes and analysis of Q value guided non-linear aspheric monovision LASIK for myopic astigmatism and presbyopia. Int Eye Sci, 2012, 12(4): 604-608. DOI: 10.3969/j.issn.1672-5123.2012. 04.02.
[19]
Alió JL, Chaubard JJ, Caliz A, et al. Correction of presbyopia by technovision central multifocal LASIK (presbyLASIK). J Refract Surg, 2006, 22(5): 453-460.