Comparison of the Efficacy of Peripheral Myopic Defocus Design and Orthokeratology Lenses to ControlAxial Elongation in Children with Myopia
Li Wei1, Ming Wang2, Shiao Yu1,Aicun Fu1
1Department of Ophthalmology, the First Affliated Hospital of Zhengzhou University, Zhengzhou 450000, China 1Department of Ophthalmology, the First Affliated Hospital of Zhengzhou University, Zhengzhou 450000, China
Abstract：Objective: To compare the effectiveness of peripheral myopic defocus design spectacle lenses (PMDSL) and orthokeratology (OK) lenses in controlling axial elongation in children with myopia. Methods: In this retrospective study, we continuously enrolled children aged 6 to 14 with myopia ranging from -6.00 to -1.00 D, who were ftted with PMDSL lenses (149 cases) or OK lenses (152 cases) at the First Affliated Hospital of Zhengzhou University between June 2020 and June 2021. They were then followed up for a period of 12 months. Subsequently, the children were divided into four subgroups based on their age (6 to 10 years old, including 10 years old; 10 to 14 years old) and median myopia (-3.00 to -1.00 D, including -3.00 D; -6.00 to -3.00 D). The t-test and multiple linear regression analysis were used to compare the axial elongation between PMDSL and OK lenses groups, as well as among the four subgroups. Results: After 12 months, the axial elongation was 0.23±0.16 mm in the PMDSL group and 0.17±0.19 mm in the OK lenses group (t=2.86, P=0.007). The multiple linear regression analysis revealed that the axial elongation in the PMDSL group was 0.04 mm more than that in the OK lenses group (β=0.04, P=0.019). In the subgroups of children aged 6 to 10 years, the axial elongation was 0.26±0.16 mm in the PMDSL group and 0.19±0.21 mm in the OK lenses group (t=2.78, P=0.009). Among children with myopia ranging from -6.00 to -3.00 D, the axial elongation in the PMDSL group was 0.21±0.13 mm, while it was 0.13±0.18 mm in the OK lenses group (t=2.92, P=0.006). The multiple linear regression analysis further demonstrated that the axial elongation in the PMDSL group was 0.05 mm (β=0.05, P=0.041) and 0.07 mm (β=0.07, P=0.039) more than that in the OK lenses group in the corresponding subgroups mentioned above. However, there was no signifcant difference between the two subgroups of children aged 10 to 14 years and those with myopia ranging from -3.00 to -1.00 D (all P>0.05). Conclusion: OK lenses were found to be more effective than PMDSL in controlling axial elongation over a one-year treatment period, especially in children with relatively younger ages and higher degrees of myopia.
魏丽, 王铭, 于世傲, 等. 离焦设计框架眼镜和角膜塑形镜控制近视儿童眼轴延长的疗效比较[J]. 中华眼视光学与视觉科学杂志, 2023, 25(7): 506-511.
Li Wei1, Ming Wang2, Shiao Yu1,et al. Comparison of the Efficacy of Peripheral Myopic Defocus Design and Orthokeratology Lenses to ControlAxial Elongation in Children with Myopia. Chinese Journal of Optometry Ophthalmology and Visual science, 2023, 25(7): 506-511. DOI: 10.3760/cma.j.cn115909-20230225-00047
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