Comparison of Six Intraocular Lens Power Calculation Formulas for a Trifocal Intraocular Lens
Qian Tan1, 3, Yong Wang1, 2
1 Aier School of Ophthalmology, Central South University, Changsha 410000, China 2 Wuhan Aier Eye Hospital, Wuhan 430000, China 3 Changsha Aier Eye Hospital, Changsha 410000, China
Objective: To evaluate the accuracy of the Barrett Universal II for calculating the power of atrifocal intraocular lens (IOL, AT LISA tri839 MP), and compare it with existing formulas (Haigis, HofferQ, SRK/T, SRK II and Holladay1). Methods: Consecutive patients who underwent phacoemulsification cataract surgery with implantation of a trifocal IOL at our institution from December 2016 to August 2018 were enrolled. Preoperative optical biometrics were measured by a Lenstar 900, and the Lenstar software was used to calculate the IOL power and predict the refractive outcome for every formula using User Group for Laser Interference Biometry (ULIB) constants. Subject manifest refraction was performed at 3 months or later postoperatively. The primary outcomes were the differences in mean absolute prediction error (MAE) between the formulas. Median and maximum absolute prediction errors (MedAE and MaxAE) were evaluated as well as the percentage of eyes within the prediction errors of ±0.5 D, ±1.0 D and ±2 D. A Kruskal-Wallis non-parameter test was used to analyze the data. Results: The study was comprised of 78 eyes of 55 patients. The formulas were ranked by the MAE as follows: Barrett Universal II (0.332 D), SRK/T (0.420 D), Haigis (0.480 D), Holladay1 (0.607 D), HofferQ (0.626 D) and SRKII (0.822 D). The differences in absolute errors with the formulas were significant (P<0.001). MaxAE of the Barrett Universal II was the lowest among all formulas. The highest percentage of eyes within the prediction errors of ±0.5 D, ±1.0 D and ±2.0 D was also obtained with the Barrett Universal II (73%, 94.8% and 100% respectively). Conclusions: The most accurate predictions of actual postoperative refraction areachieved using the Barrett Universal II, SRK/T and Haigis formulas. Thus, one of these formulas should be used for the IOL power calculation of atrifocal IOL.
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