Abstract:Objective: To observe the changes in choroidal thickness (CT) and axial length (AL) before and after wearing orthokeratology lenses and to investigate the role of the choroid in slowing the progression of myopia. Methods: This was a self-control study. From August 2018 to June 2019, in which 26 monocular myopic adolescents (52 eyes) who were treated with orthokeratology lenses in Shenyang Aier Eye Hospital were recruited. The eyes fitted with orthokeratology lenses served as the experimental group, while the fellow eyes without treatment served as the control group. AL and CT were measured in both groups at baseline and the 6-month visit. A paired t-test was used to analyze AL and CT before and after wearing orthokeratology lenses and the changes were compared between the 2 groups. Results: After 6 months of wearing orthokeratology lenses, the CT of the experimental group increased in all positions (all P<0.05), and the CT of the control group decreased in all positions (all P<0.05). There was a statistically significant difference in the changes in CT between the 2 groups before and after wearing orthokeratology lenses (all P<0.05). The AL in both groups increased significantly (both P<0.05). AL elongation was 0.09±0.15 mm in the experimental group and 0.26±0.16 mm in the control group, and there was a statistically significant difference between the 2 groups (t=-4.024, P<0.001). Conclusions: For myopic adolescents, wearing orthokeratology lenses can thicken the choroid and slow axial growth, which may be one of the reasons for using orthokeratology lenses to control the progression of myopia.
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