Comparative Study of the Progression of Low to Moderate Myopia in Children 6−12 Years of Age in the Xi'an First Hospital before and after the Outbreak of COVID-19" />
Comparative Study of the Progression of Low to Moderate Myopia in Children 6−12 Years of Age in the Xi'an First Hospital before and after the Outbreak of COVID-19
Pan Li, Tong Li, Jin Wang, Ruoxin Wang, Xuehui Zhang
Department of Ophthalmology, Xi'an First Hospital, Institute of Ophthalmology, Key Lab of Ophthalmology, Clinical Center for Ophthalmology, Xi'an 710002, China
Objective: To compare the progression of low to moderate myopia in children 6-12 years of age in
the Xi'an First Hospital before and after the COVID-19 epidemic. Methods: This was a retrospective
cohort study. One hundred cases (200 eyes) of children 6-12 years of age with binocular myopia who
were admitted to the Department of Ophthalmology in Xi'an No.1 Hospital before the outbreak of the COVID-19 epidemic (December 2018 to January 2019) and after the outbreak (December 2019 to January
2020) participated in the study. Follow-up records were recorded for 0.5 and 1 year. The mean age of the
pre-epidemic group was 9.6±1.2 years, and the mean age of the post-epidemic group was 9.2±2.4 years.
Changes in the ocular axis (AL), spherical equivalent (SE) and axial/corneal curvature ratio (AL/CR) at
baseline, 0.5 and 1 year were retrospectively analyzed in the 2 groups, and the data were compared by a
paired t test. Results: At the 0.5 year follow-up, the pre-epidemic group showed less AL growth than the
post-epidemic group (0.27±0.16 mm vs. 0.36±0.19 mm) (t=-6.228, P<0.001), an increase in SE (-0.48±
0.37 D vs. -0.74±0.63 D) (t=-2.375, P<0.001), and an increase in AL/CR ratio (0.017±0.028 vs.
0.029±0.031) (t=-6.052, P<0.001). At the 1 year follow-up, the pre-epidemic group showed less AL growth
than the post-epidemic group (0.46±0.31 vs. 0.61±0.24) (t=1.138, P<0.001), an increase in SE (-0.90±
0.41 D vs. -1.25±0.48 D) (t=7.253, P<0.001), and an increase in the AL/CR ratio (0.030±0.051 vs.
0.046±0.036) (t=5.049, P=0.032). Conclusions: After the outbreak of COVID-19, the progression of
myopia in 6-12 year-old school-age children in the post-epidemic is faster than in the pre-epidemic, mainly
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Pan Li, Tong Li, Jin Wang, et al. Comparative Study of the Progression of Low to Moderate Myopia in Children 6−12 Years of Age in the Xi'an First Hospital before and after the Outbreak of COVID-19. Chinese Journal of Optometry Ophthalmology and Visual science, 2021, 23(12): 910-917. DOI: 10.3760/cma.j.cn115909-20210519-00197
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