Objective To observe the safety and efficacy of liquid infiltration method to separate lenticule in small incision lenticule extraction (SMILE). Methods In this prospective study, 72 patients were included. Randomly selected one eye was performed conventional method; the contralateral eye was performed liquid infiltration method. The corneal epithelium injury around the incision in surgery and the smoothness of the lenticule edge was observed under optical microscope. The differences of visual acuity, refraction, contrast sensitivity postoperatively between the two groups using independent samples t test. Results The corneal epithelium injuries were observed in 2 eyes in liquid infiltration method and 14 eyes in conventional method during surgery, the difference was statistically significant (χ2=6.41, P<0.01), the lenticule edges of liquid infiltration method were smoother than conventional method. The visual acuity, spherical equivalent (SE) and residual astigmatism of liquid infiltration method and conventional method 1 day postoperative were: 4.98±0.06 and 4.89±0.53, +0.20±0.42 D and +0.30±0.37 D, 0.14±0.40 D and 0.41±0.57 D respectively. The difference of residual astigmatism was statistically significant(t=-3.29, P<0.05). The visual acuity, spherical equivalent and residual astigmatism of liquid infiltration method and conventional method 1 month postoperative were: 4.99±0.06 and 4.97±0.06, +0.11±0.40 D and +0.13±0.41 D, 0.05±0.46 D and +0.36±0.66 D, respectively. The difference of residual astigmatism was statistically significant (t=-3.41, P<0.05). The difference of contrast sensitivity was without statistically significant. Conclusion The liquid infiltration method makes the edge of lenticule smoother and effectively reduces the corneal epithelial injury and residual astigmatism. It is a safe and feasible skill in SMILE.
张国伟,陈开建,白继,阚秋霞,刘丽娜,许多,郎敏. 水浸润分离法在SMILE手术角膜基质透镜分离中的应用[J]. 中华眼视光学与视觉科学杂志, 2014, 16(7): 412-415.
Zhang Guowei,Chen Kaijian,Bai Ji,Kan Qiuxia,Liu Lina,Xu Duo,Lang Min. Liquid infiltration method to separate lenticule in small incision lenticule extraction. Chinese Journal of Optometry Ophthalmology and Visual science, 2014, 16(7): 412-415. DOI: 10.3760/cma.j.issn.1674-845X.2014.07.007
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